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Overview

Uniprot IDA0A287AZY8
Protein NamePolyadenylate-binding protein 5
Gene NamePABPC5
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
239 RDASGKSKGFGFVRY

Function

Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo

Protein Sequence

10 MGSGEPNPAG 20 KKKKYLKAAL 30 YVGDLAPDVT 40 EDMLYKKFRP 50 AGPLRFTRIC 60 RDPVTRSPLG 70 YGYVNFRFPA 80 DAEWALNTMN 90 FDLINGKPFR 100 LMWSQPDDRL 110 RKSGVGNIFI 120 KNLDKSIDNR 130 ALFYLFSAFG 140 NILSCKVVCD 150 DNGSKGYAYV 160 HFDSLAAANR 170 AIWHMNGVRL 180 NNRQVYVGRF 190 KFPEERAAEV 200 RTRDRATFTN 210 VFVKNFGEDM 220 DDDKLKEIFS 230 EYGPTESVKV 240 IRDASGKSKG 250 FGFVRYETHE 260 AAQKAVLDLH 270 GKSIDGKVLY 280 VGRAQKKIER 290 LAELRRRFER 300 LRLKEKSRPP 310 GVPIYIKNLD 320 ETIDDEKLKE 330 QFSSFGSITR 340 AKVMVEVGQG 350 KGFGVVCFSS 360 FEEATKAVDE 370 MNGRVVGSKP 380 LHVTLGQARR RW

Gene Ontology

Classification GO ID Description
Cellular Component GO:0010494 cytoplasmic stress granule
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005634 nucleus
Cellular Component GO:1990904 ribonucleoprotein complex
Molecular Function GO:0003730 mRNA 3'-UTR binding
Molecular Function GO:0008143 poly(A) binding
Molecular Function GO:0008266 poly(U) RNA binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.