Search Results

Overview

Uniprot ID	A0A287B0D1
Protein Name	Protein unc-45 homolog B
Gene Name	UNC45B
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
39	ALKLTKDKALQATLY
603	VQLAKFSKQHVPEEH

Function

Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development

Protein Sequence

10 MAEAEAVQLK 20 EEGNRHFQLQ 30 DYKAATESYS 40 QALKLTKDKA 50 LQATLYRNRA 60 ACGLKTESYV 70 QAASDASRAI 80 DINSSDIKAL 90 YRRCQALEHL 100 GKLDQAFKDV 110 QRCATLEPRN 120 QNFQETLRRL 130 NTSIQEKLRV 140 QFSTDSRVQK 150 MFEILLDPNS 160 EADLLEKAAN 170 NLIVLGREEA 180 GAERIFQNNG 190 VALLLQLVDT 200 KRPELMLAAV 210 RTLSGMCSGH 220 RARATAILHA 230 VRIDRICSLM 240 AVENEEMSLA 250 VCNLLQAIID 260 ALSGEDKREH 270 RGKEEALVLD 280 TKKDLKQITN 290 HLLDMLVSKK 300 VSGQGRDQAL 310 NLLNKNVPRK 320 DLAIHDNSRT 330 IYVVDNGLRK 340 ILKVVGQVPD 350 LPSCLPLTDH 360 TRMLASILIN 370 KLYDDLRCDP 380 ERDHFRKICE 390 EYITGKFDPQ 400 DMDKNVIAIQ 410 TVSGILQGPF 420 DLGNQLLSLK 430 GVMEMMVALC 440 GSERETDQLV 450 AVEALIHAST 460 KLSRATFIIT 470 NGVALLKELY 480 KTTKNEKIKI 490 RTLVGLCKLG 500 SAGGTDYGLR 510 QFAEGSTEKL 520 AKQCRKWLCN 530 AAIDTRTRRW 540 AVEGLAYLTL 550 DADVKDDFVQ 560 DIPALQAMFE 570 LAKASTPDKT 580 ILYSVATTLV 590 NCTNSYDVKE 600 VIPELVQLAK 610 FSKQHVPEEH 620 PKDKKDFVDM 630 RVKRLLKAGV 640 ISALACMVKA 650 DNAILTDQTK 660 ELLARVFLAL 670 CENPKDRGTI 680 VAQGGGKALI 690 PLALEGTDVG 700 KVKAAHALAK 710 IAAISNPDIA 720 FPGERVYEVV 730 RPLVRLLDTQ 740 RDGLQNYEAL 750 LGLTNLSGRS 760 DKLRQKIFKE 770 KALPDIENYM 780 FENHDQLRQA 790 ATECMCNMVV 800 NKEVQERFLA 810 DGNDRLKLVV 820 LLCGEDDDKV 830 QNAAAGALAM 840 LTAAHKKLCF 850 KMTQVTTQWL 860 EILQRLCLHD 870 RLSVQHRGLV 880 IAYNLLAADA 890 ELAKKLVESE 900 LLEILTVVSK 910 QEPDEKKAAV 920 VQTARECLIK 930 CMDYGFIKPV S

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0031672	A band
Cellular Component	GO:0005737	cytoplasm
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0048471	perinuclear region of cytoplasm
Cellular Component	GO:0030018	Z disc
Molecular Function	GO:0051879	Hsp90 protein binding
Biological Process	GO:0030154	cell differentiation
Biological Process	GO:0007517	muscle organ development
Biological Process	GO:0006457	protein folding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.