Search Results
Overview
| Uniprot ID | A0A287B2P7 |
|---|---|
| Protein Name | Phosphatidylinositol-glycan biosynthesis class X protein |
| Gene Name | PIGX |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 72 | RDLLIRVKFGEGIED |
Function
Stabilizing subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM
Protein Sequence
10
MVGFFFFFFF
20
HFTSWFISMP
30
CIMRVQLRRA
40
IASLQTSRNS
50
GFGGIRATCS
60
EIILKQEVLK
70
DGFHRDLLIR
80
VKFGEGIEDL
90
QTCRVLIRQY
100
IPTGLFVDPY
110
ELASLREKNI
120
TEAVMVSENF
130
NIEAPDYLSK
140
ESEVLIYARQ
150
DPQCTDCFQA
160
FLPVHYRYHR
170
PHCNDEETFI
180
VVNNPDLLMY
190
CDQEFPVLKC
200
WTQSEMTAPC
210
ALNSQDICQW
220
NNMKYKSVYK
230
NVTLLVPVGL
240
TIHTSLVCSV
250
TLLVTVLCSA
260
LILVAVFTYG
HFSL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Biological Process | GO:0006506 | GPI anchor biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.