Search Results
Overview
| Uniprot ID | A0A287B2X0 |
|---|---|
| Protein Name | Copine-3 |
| Gene Name | CPNE3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 114 | FEVVQKLKFGIYDID |
| 222 | VHRTEVIKNNLNPVW |
| 291 | EFECINEKKKQKKKS |
| 300 | KQKKKSYKNSGIISV |
| 90 | VERTERIKNCLNPKF |
| 96 | IKNCLNPKFSKTFII |
Function
Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation
Protein Sequence
10
MDKTIFKCLL
20
LLSMCVDWKE
30
EFSGFKARRR
40
KDKFAELEMA
50
AQCVTKVELN
60
ISCDNLLDKD
70
VGSKSDPLCV
80
LFLNTSGQQW
90
YEVERTERIK
100
NCLNPKFSKT
110
FIIDYYFEVV
120
QKLKFGIYDI
130
DNKTIELSDD
140
DFLGEFECTL
150
GQIVSSKKLT
160
RPLVLKNGRP
170
AGKGSITISA
180
EEIKDNRVVL
190
FEMEARKLDN
200
KDLFGKSDPY
210
LEFHKQTSDG
220
NWLMVHRTEV
230
IKNNLNPVWR
240
PFKISLNSLC
250
YGDMDKTIKV
260
ECYDYDNDGS
270
HDLIGTFQTT
280
MTKLKEASRN
290
SPIEFECINE
300
KKKQKKKSYK
310
NSGIISVKQC
320
EITVECTFLD
330
YVMGGCQLNF
340
TVGVDFTGSN
350
GDPRSPNSLH
360
YISPNGVNEY
370
LTAIWSVGLV
380
IQDYDADKMF
390
PAFGFGAQIP
400
PQWQVSHEFP
410
INFNPSNPYC
420
NGIQGIIEAY
430
RACLPQIKLY
440
GPTNFSPIIN
450
HVAKFAAAAT
460
QQHTASQYFV
470
LLIITDGVIT
480
DLDETRQAIV
490
NAAKLPMSII
500
IVGVGGADFS
510
AMEFLDADGG
520
SLRSPSGEVA
530
IRDIVQFVPF
540
RQFQNAPKEA
550
LAQCVLAEIP
560
QQVVGYFNAY
570
KLLPPKNPAA
K
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0005544 | calcium-dependent phospholipid binding |
| Molecular Function | GO:0048306 | calcium-dependent protein binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004674 | protein serine/threonine kinase activity |
| Molecular Function | GO:0030971 | receptor tyrosine kinase binding |
| Biological Process | GO:0071277 | cellular response to calcium ion |
| Biological Process | GO:0071363 | cellular response to growth factor stimulus |
| Biological Process | GO:0038128 | ERBB2 signaling pathway |
| Biological Process | GO:0030335 | positive regulation of cell migration |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.