Search Results
Overview
| Uniprot ID | A0A287B2Z6 |
|---|---|
| Protein Name | Zinc finger protein 22 |
| Gene Name | ZNF22 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 174 | YQCGECGKCFSQSSH |
| 205 | RGKNIRAKAHLVSSW |
| 53 | LRRSLDEKPYKCTEC |
Function
Binds DNA through the consensus sequence 5'-CAATG-3'. May be involved in transcriptional regulation and may play a role in tooth formation
Protein Sequence
10
MRFGKPKGGI
20
SRSSSQGKAY
30
ENQHKTGRQR
40
QKWGVTVRFD
50
SGLSRLRRSL
60
DEKPYKCTEC
70
EKSFSQSSTL
80
FQHQKIHTGK
90
KSHKCADCGK
100
SFFQSSNLIQ
110
HRRIHTGEKP
120
YKCDECGERF
130
KQSSNLIQHQ
140
RIHTGEKPYQ
150
CDECGRCFSQ
160
SSHLIQHQRT
170
HTGEKPYQCG
180
ECGKCFSQSS
190
HLRQHMKVHK
200
EEKPRKTRGK
210
NIRAKAHLVS
220
SWKAGKGRKS
VARLR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:0001817 | regulation of cytokine production |
| Biological Process | GO:0002682 | regulation of immune system process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.