Search Results

Overview

Uniprot IDA0A287B4E6
Protein NameTranslationally-controlled tumor protein
Gene NameTPT1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
102 YMKSIKGKLEEQRPE
93 EAYKKYIKDYMKSIK
97 KYIKDYMKSIKGKLE

Function

Involved in calcium binding and microtubule stabilization. Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein

Protein Sequence

10 MIIYRDLISH 20 DEMFSDIYKI 30 REIADGLCLE 40 VEGKMVSRTE 50 GNIDDSLIGG 60 NASAEGPEGE 70 GTESTVITGV 80 DIVMNHHLQE 90 TSFTKEAYKK 100 YIKDYMKSIK 110 GKLEEQRPER 120 VKPFMTGAAE 130 QIKHILANFK 140 NYQFFIGENM 150 NPDGMVALLD 160 YREDGVTPYM 170 IFFKDGLEME 180 KCVSTKKWVE 190 ISNVKMESVG 200 IIPCFMPLGQ 210 LEWVLQQSFE 220 NEGAGLFSWG 230 SKECCDSHVK 240 DFYGIEKLRM DLQET

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005881 cytoplasmic microtubule
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005615 extracellular space
Cellular Component GO:0005771 multivesicular body
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0000922 spindle pole
Molecular Function GO:0005509 calcium ion binding
Molecular Function GO:0140297 DNA-binding transcription factor binding
Biological Process GO:2000384 negative regulation of ectoderm development
Biological Process GO:0009615 response to virus
Biological Process GO:0019827 stem cell population maintenance

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.