Search Results

Overview

Uniprot IDA0A287B4T1
Protein NameNAD-dependent protein deacetylase sirtuin-2
Gene NameSIRT2
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
214 TLGWMKEKIFSEVTP

Function

No function data available.

Protein Sequence

10 MAEPDPSDPV 20 ETQTGKVQEA 30 QDSDSDSDTE 40 EGAAGGEAEM 50 DFLRNFFSQT 60 LGLGTQKERL 70 LDELTLEGVS 80 RYMQSERCRR 90 VICLVGAGIS 100 TCRGIPDFRS 110 PSTGLYANLE 120 KYRLPYPEAI 130 FEIGYFKKHP 140 EPFFALAKEL 150 YPGQFKPTIC 160 HYFIRLLKEK 170 GLLLRCYTQN 180 IDTLERVAGL 190 EPEDLVEAHG 200 TFYTSHCISP 210 LCRQEYTLGW 220 MKEKIFSEVT 230 PKCEKCQSVV 240 KPDIVFFGEN 250 LPARFFSCMQ 260 SDFLKVDLLI 270 VMGTSLQVQP 280 FASLISKAPL 290 STPRLLINKE 300 KTGQTDPFLG 310 MMMGLGGGMD 320 FDSKKAYRDV 330 AWLGDCDQGC 340 LALADLLGWK 350 KELEDLVRKE 360 HASIDAQSGS 370 GTPNPTTSAS 380 PRKSPPPAKA 390 EARTSEGEKP Q

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005814 centriole
Cellular Component GO:0005694 chromosome
Cellular Component GO:0030426 growth cone
Cellular Component GO:0005874 microtubule
Cellular Component GO:0030496 midbody
Cellular Component GO:0043209 myelin sheath
Cellular Component GO:0005634 nucleus
Cellular Component GO:0048471 perinuclear region of cytoplasm
Cellular Component GO:0005819 spindle
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0070403 NAD+ binding
Molecular Function GO:0140773 NAD-dependent protein demyristoylase activity
Molecular Function GO:0140774 NAD-dependent protein depalmitoylase activity
Molecular Function GO:0034979 NAD-dependent protein lysine deacetylase activity
Molecular Function GO:0042903 tubulin deacetylase activity
Biological Process GO:0051301 cell division
Biological Process GO:0051093 negative regulation of developmental process
Biological Process GO:0051239 regulation of multicellular organismal process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.