Search Results
Overview
| Uniprot ID | A0A287B4U1 |
|---|---|
| Protein Name | Rab GDP dissociation inhibitor |
| Gene Name | GDI1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 175 | VEGSFVYKGGKIYKV |
| 332 | NGKVVGVKSEGEVAR |
| 341 | EGEVARCKQLICDPS |
| 356 | YVPDRVRKAGQVIRI |
Function
Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP
Protein Sequence
10
MLSSLFTFLP
20
SKVMRGSHGQ
30
MKCPPLHFQP
40
GDQPGMEGAV
50
RRGQGPSRFA
60
VSALGWRARQ
70
GCLGDREVGG
80
QWTLLLAQEC
90
ILSGIMSVNG
100
KKVLHMDRNP
110
YYGGESSSIT
120
PLEELYKRFQ
130
LLEGPPEAMG
140
RGRDWNVDLI
150
PKFLMANGQL
160
VKMLLYTEVT
170
RYLDFKVVEG
180
SFVYKGGKIY
190
KVPSTETEAL
200
ASNLMGMFEK
210
RRFRKFLVFV
220
ANFDENDPKT
230
FEGVDPQSTS
240
MRDVYRKFDL
250
GQDVIDFTGH
260
ALALYRTDDY
270
LDQPCLETIN
280
RIKLYSESLA
290
RYGKSPYLYP
300
LYGLGELPQG
310
FARLSAIYGG
320
TYMLNKPVDD
330
IIMENGKVVG
340
VKSEGEVARC
350
KQLICDPSYV
360
PDRVRKAGQV
370
IRIICILSHP
380
IKNTNDANSC
390
QIIIPQNQVN
400
RKSDIYVCMI
410
SYAHNVAAQG
420
KYIAIASTTV
430
ETAEPEKEVE
440
PALELLEPID
450
QKFVAISDLY
460
EPVDDGSESQ
470
VFCSCSYDAT
480
THFETTCNDI
490
KDIYKRMVGS
500
AFDFENMKRR
510
GGKADFCPHR
S
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005794 | Golgi apparatus |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0005093 | Rab GDP-dissociation inhibitor activity |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0007264 | small GTPase-mediated signal transduction |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.