Search Results
Overview
| Uniprot ID | A0A287B4Y1 |
|---|---|
| Protein Name | Endoplasmic reticulum resident protein 44 |
| Gene Name | ERP44 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 144 | RVFERVAKILHDDCT |
| 264 | FLHADCDKFRHPLLH |
| 274 | HPLLHIQKTPADCPV |
| 304 | RDVLIPGKLKQFVFD |
| 306 | VLIPGKLKQFVFDLH |
| 67 | AQRYRISKYPTLKLF |
| 91 | YRGQRSVKALADYIR |
Function
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum
Protein Sequence
10
MKEPLESKRL
20
KIQIVSPWCR
30
FSQMLHPIFE
40
EASNVIKEEY
50
PNENQVVFAR
60
VDCDQHSDIA
70
QRYRISKYPT
80
LKLFRNGMMM
90
KREYRGQRSV
100
KALADYIRQQ
110
KSDPIQELHD
120
LAEITTLDRS
130
KRNIIGYFEQ
140
KDSENYRVFE
150
RVAKILHDDC
160
TFLSAFGAVS
170
KPERYSGDNI
180
VYKPPGHSAP
190
DMVYLGYMTN
200
FDGTFNWIQD
210
KCVPLVREIT
220
FENGEELTEE
230
GLPFLILFHM
240
KEDTESLEIF
250
QNEVARQLIS
260
EKGTINFLHA
270
DCDKFRHPLL
280
HIQKTPADCP
290
VIAIDSFRHM
300
YVFGDFRDVL
310
IPGKLKQFVF
320
DLHSGKLHRE
330
FHHGPDPTDT
340
APGQEVQDVA
350
SSPPESSFQK
360
LAPSEYRYTL
LRDRDEL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0005788 | endoplasmic reticulum lumen |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.