Search Results
Overview
| Uniprot ID | A0A287B5I0 |
|---|---|
| Protein Name | Filamin-binding LIM protein 1 |
| Gene Name | FBLIM1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 247 | CYQDTLEKCGKCGEG |
| 250 | DTLEKCGKCGEGVRE |
| 303 | CLDDFYRKFAPVCSI |
| 366 | LNNRLFCKPCHVKRS |
| 50 | RESPVPVKAPGAGSA |
Function
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion
Protein Sequence
10
MASKPEKRVA
20
SSVFITLAPP
30
RRDEAVVEEV
40
KRAACEARPG
50
CPRESPVPVK
60
APGAGSAGRL
70
RSWAPPGRAS
80
APVPAVPPQL
90
SNGGCSLPPP
100
PLDGEDSLPD
110
LDLLPPPPPP
120
PPPMYLPPPD
130
QEPPASVGAL
140
VSDLEQLHLP
150
PPPPPPQALV
160
EGPPLQPQPS
170
PLRPMEELPP
180
PPEEPVSLPE
190
REASTDICAF
200
CHKTVSPREL
210
AVEAMKRQYH
220
AQCFTCRVCR
230
RQLAGQSFYQ
240
KDGRPLCEPC
250
YQDTLEKCGK
260
CGEGVREHII
270
RALGQAFHPT
280
CFTCVTCARC
290
IGDESFALDS
300
QNEVYCLDDF
310
YRKFAPVCSI
320
CENPIIPRDG
330
KDAFKIECMG
340
RNFHENCYRC
350
EDCRILLSVE
360
PTDQGCYPLN
370
NRLFCKPCHV
KRSAASCC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0001725 | stress fiber |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0007155 | cell adhesion |
| Biological Process | GO:0008360 | regulation of cell shape |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.