Search Results

Overview

Uniprot ID	A0A287B642
Protein Name	Torsin-1A-interacting protein 1
Gene Name	TOR1AIP1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
585	VQPENDLKRGICL**

Function

Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina

Protein Sequence

10 MGGVRHAQGP 20 LREGRSRLAP 30 QNGGGSDAPA 40 YGTPTPPRHS 50 RREVRFSEEP 60 PEVYGDFEPR 70 AAKEKVPVGR 80 QIPLEEFRPD 90 SAKEEVRESA 100 YYLRSRRQRQ 110 PRLPEAEEMK 120 TRRGTRLQQQ 130 QQQPHSQPPP 140 LQSSPVTTRR 150 GLRDSHSSEE 160 DETPSQTVLS 170 QTVSKKTIMR 180 TQETPVVSED 190 PVISLRRPPL 200 RSSRSEATSV 210 QQKVNFSEEG 220 ETEENDQDSS 230 DSDVTTVKFR 240 SRDSVASGDQ 250 TTRSSSQYPE 260 SLWQSSQSGD 270 FITLDKQPLV 280 LSSGYQKNPQ 290 QWVEQTTRIR 300 TRMQTSSPGK 310 RSIYGSFSDD 320 DSVQKPELGN 330 QSPSTSSQQV 340 TGQAKTTSFF 350 KIKWWWFPVV 360 IVALAIGNFW 370 FSRTSEAETT 380 AVQEFQNQMK 390 QLMNKYQGQD 400 EKLWRRSQTF 410 LEKHLNSSQP 420 RPQPAILLLT 430 AARDAEEALK 440 CLSEQIADAY 450 SSFRSVPAIR 460 IDGAGKATQD 470 SDIVKQEVDE 480 ELSNGFKNGQ 490 NAAVVHRFES 500 LPAGSTLIFY 510 KYCDHENAAF 520 KDVALVLTVL 530 LEEETLGTSL 540 GLKEIEEKVR 550 DFLQVKFTNS 560 DTPDSYKHMD 570 PDKLNGLWSR 580 ISHLVLPVQP 590 ENDLKRGICL

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005637	nuclear inner membrane
Cellular Component	GO:0031965	nuclear membrane
Molecular Function	GO:0001671	ATPase activator activity
Molecular Function	GO:0051117	ATPase binding
Molecular Function	GO:0008092	cytoskeletal protein binding
Biological Process	GO:0071763	nuclear membrane organization

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.