Search Results
Overview
| Uniprot ID | A0A287B6J3 |
|---|---|
| Protein Name | RNA-binding protein PNO1 |
| Gene Name | PNO1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 125 | IRTCKETKDVSALTK |
| 191 | AGKGGKTKFTIENVT |
Function
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA
Protein Sequence
10
METQMEAQSP
20
LAEDGFTQVT
30
RKGSRRAKKR
40
QAEQLSATEE
50
GGGASHMDTE
60
EARPAKRPIF
70
PPLSGDGFLS
80
GKEETRKIPV
90
PANRYTPLKE
100
NWMKIFTPIV
110
EHLGLQIRFN
120
LKSRNVEIRT
130
CKETKDVSAL
140
TKAADFVKAF
150
ILGFQVEDAL
160
ALVRLDDLFL
170
ETFEITDVKP
180
LKGDHLSRAI
190
GRIAGKGGKT
200
KFTIENVTRT
210
RIVLADVKVH
220
ILGSFQNIKM
230
ARTAICNLIL
240
GNPPSKVYGN
250
IRAVASRAAD
RF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0032040 | small-subunit processome |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0042274 | ribosomal small subunit biogenesis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.