Search Results
Overview
| Uniprot ID | A0A287B6T6 |
|---|---|
| Protein Name | Mevalonate kinase |
| Gene Name | MVK |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 249 | TKVPRSTKALVASVR |
Function
Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis
Protein Sequence
10
LGIYHMIPRS
20
HVVSSPAGVR
30
SRESHPSWRA
40
FCGPWQALAV
50
ALNLRTFLRL
60
QPHNSGKVSL
70
RLPNIGIQQT
80
WDVARLQLLD
90
TSFLEQGDLT
100
EQVEKLKEVA
110
GFSKDSTNHD
120
CLAVPAFLYL
130
YLTICRSQRT
140
LPSLDIAVWS
150
ELPTGAGLGS
160
SAAYSVCLAA
170
ALLTACEEIP
180
NPLKDGEATG
190
RWTEENLELI
200
NKWAFQGERV
210
IHGNPSGVDN
220
AVSTWGGALR
230
YQQGKISPLK
240
RLPTLEILLV
250
NTKVPRSTKA
260
LVASVRNRML
270
KFPEIIAPLL
280
ASMDAISLEC
290
ERVLGEMAAA
300
PALEHYLVLE
310
ELIDMNQHHL
320
NALGVGHASL
330
DQLCQVTTAH
340
GLHSKLTGAG
350
GGGCGITLLR
360
PDLERPEVED
370
TKQALTSCGF
380
DCWETSIGAP
390
GVFVHMAASL
400
DASVQQALGD
LR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005777 | peroxisome |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004496 | mevalonate kinase activity |
| Biological Process | GO:0006695 | cholesterol biosynthetic process |
| Biological Process | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.