Search Results
Overview
| Uniprot ID | A0A287B6U9 |
|---|---|
| Protein Name | YTH domain-containing family protein |
| Gene Name | YTHDF3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 403 | CSTEHGNKRLDAAYR |
Function
Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing
Protein Sequence
10
MMNNSYPPMS
20
DPYMPSYYAP
30
SIGFPYSLGE
40
AAWSTAGDQP
50
MPYLTTYGQM
60
SNGEHHYIPD
70
GVFSQPGALG
80
NTPPFLGQHG
90
FNFFPGNADF
100
STWGTSGSQG
110
QSTQSSAYSS
120
SYGYPPSSLG
130
RAITDGQAGF
140
GNDTLSKVPG
150
ISSIEQGMTG
160
LKIGGDLTAA
170
VTKTVGTALS
180
SSGMTSIATN
190
SVPPVSSAAP
200
KPTSWAAIAR
210
KPAKPQPKLK
220
PKGNVGIGGS
230
AVPPPPIKHN
240
MNIGTWDEKG
250
SVVKAPPTQP
260
VLPPQTIIQQ
270
PQPLIQPPPL
280
VQSQLPQQQP
290
QPPQPQQQQG
300
PQPQAQPHQV
310
QPQQQQLQNR
320
WVAPRNRGAG
330
FNQNNGAGGE
340
NFGLGVVPVS
350
ASPSSVEVHP
360
VLEKLKAINN
370
YNPKDFDWNL
380
KNGRVFIIKS
390
YSEDDIHRSI
400
KYSIWCSTEH
410
GNKRLDAAYR
420
SLNGKGPLYL
430
LFSVNGSGHF
440
CGVAEMKSVV
450
DYNAYAGVWS
460
QDKWKGKFEV
470
KWIFVKDVPN
480
NQLRHIRLEN
490
NDNKPVTNSR
500
DTQEVPLEKA
510
KQVLKIIATF
520
KHTTSIFDDF
530
AHYEKRQEEE
540
EAMRRERNRN
KQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0010494 | cytoplasmic stress granule |
| Cellular Component | GO:0000932 | P-body |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:1990247 | N6-methyladenosine-containing RNA reader activity |
| Biological Process | GO:0061157 | mRNA destabilization |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.