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Overview

Uniprot IDA0A287B794
Protein NameSarcolemmal membrane-associated protein
Gene NameSLMAP
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
458 AQSEIEAKQEIQHLR
466 QEIQHLRKELIEAQE
505 NQVEESNKQIQVLQA
528 IENLREEKDSEITST
583 AELERWRKAASEYEK
623 RLRGELEKLRKEWNV
626 GELEKLRKEWNVLET
640 TECRSLRKENVLLSS
678 SILQMTRKELENQVG
704 DLKTLLSKAENQAKD
710 SKAENQAKDVQKEYE
714 NQAKDVQKEYEKTQT
718 DVQKEYEKTQTVLSE
727 QTVLSELKLKFEMTE
745 QSITDELKQCKDNLK
752 KQCKDNLKLLREKGN

Function

Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion

Protein Sequence

10 MPSALAIFTC 20 RPNSHPFQER 30 HVYLDEPIKI 40 GRSVARCRPA 50 QNNATFDCKV 60 LSRNHALVWF 70 DHKTGKFYLQ 80 DTKSSNGTFI 90 NSQRLSRGSE 100 ESPPCEILSG 110 DIIQFGVDVT 120 ENTRKVTHGC 130 IVSTIKLFLP 140 DGMEARLRSD 150 VIHAPLPSPV 160 DKVAANTPSM 170 YSQELFQLSQ 180 YLQEALHREQ 190 MLEQKLATLQ 200 RLLAITQEAS 210 DTSWQALIDE 220 DRLLSRLEVM 230 GNQLQACSKN 240 QTEDSLRKEL 250 IALQEDKHNY 260 ETTAKESLRR 270 VLQEKIDVVR 280 KLSEVERSLS 290 NTEDECTHLK 300 EMNERTQEEL 310 RELANKYNGA 320 VNEIKDLSDK 330 LKVAEGKQEE 340 IQQKGQAEKK 350 ELQHKIDEME 360 EKEQELQAKI 370 EALQADNDFT 380 NERLTALQEK 390 LIVEGHLTKV 400 VEETKLSKEN 410 QARAKESDLS 420 DTLSPSKEKS 430 SDDTTDAQMD 440 EQDLNEPLAK 450 VSLLKDDLQG 460 AQSEIEAKQE 470 IQHLRKELIE 480 AQELARASKQ 490 KCFELQALLE 500 EERKAYRNQV 510 EESNKQIQVL 520 QAQLQRLHIN 530 IENLREEKDS 540 EITSTRDELL 550 SARDEILLLH 560 QAAKKAASER 570 DTDIASLQEE 580 LKKVRAELER 590 WRKAASEYEK 600 EITSLQNSFQ 610 LRCQQCEDQQ 620 REEATRLRGE 630 LEKLRKEWNV 640 LETECRSLRK 650 ENVLLSSELQ 660 RQEKELHNSQ 670 KQSLELTSDL 680 SILQMTRKEL 690 ENQVGSLKEQ 700 HLRDSADLKT 710 LLSKAENQAK 720 DVQKEYEKTQ 730 TVLSELKLKF 740 EMTEQEKQSI 750 TDELKQCKDN 760 LKLLREKGNN 770 KPWPWMPMLA 780 ALVAVTAIVL 790 YVPGLARASP

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005813 centrosome
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0031966 mitochondrial membrane
Cellular Component GO:0042383 sarcolemma

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.