Search Results
Overview
| Uniprot ID | A0A287B7C6 |
|---|---|
| Protein Name | Transformer-2 protein homolog beta |
| Gene Name | TRA2B |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 197 | RVDFSITKRPHTPTP |
Function
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA
Protein Sequence
10
MSDSGEQNYG
20
ERESRSASRS
30
GSAHGSGKSA
40
RHTPARSRSK
50
EDSRRSRSKS
60
RSRSESRSRS
70
RRSSRRHYTR
80
SRSRSRSHRR
90
SRSRSYSRDY
100
RRRHSHSHSP
110
MSTRRRHVGN
120
RANPDPNCCL
130
GVFGLSLYTT
140
ERDLREVFSK
150
YGPIADVSIV
160
YDQQSRRSRG
170
FAFVYFENVD
180
DAKEAKERAN
190
GMELDGRRIR
200
VDFSITKRPH
210
TPTPGIYMGR
220
PTYGSSRRRD
230
YYDRGYDRGY
240
DDRDYYSRSY
R
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.