Search Results
Overview
| Uniprot ID | A0A287B859 |
|---|---|
| Protein Name | Splicing regulatory glutamine/lysine-rich protein 1 |
| Gene Name | SREK1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 100 | VVPCAEGKIPEEAKA |
Function
Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3
Protein Sequence
10
MNSGGGFGLG
20
LGFGLTPTAV
30
IQVTNLSSAV
40
TSEQMRTLFS
50
FLGEIEELRL
60
YPPDNAPLAF
70
SSKVCYVKFR
80
DPSSVGVAQH
90
LTNTVFIDRA
100
LIVVPCAEGK
110
IPEEAKALSL
120
LAPAPTMTGL
130
MPGAGLLPIP
140
TPNPLTTLGV
150
SLSSLGAIPA
160
AALDPNIATL
170
GEIPQPPLMG
180
NVDPSKIDEI
190
RRTVYVGNLN
200
SQTTTADQLL
210
EFFKQVGEVK
220
FVRMAGDETQ
230
PTRFAFVEFA
240
DQNSVPRALA
250
FNGVMFGDRP
260
LKINHSNNAI
270
VKPPEMTPQA
280
AAKELEEVMK
290
RVREAQSFIS
300
AAIEPESGKS
310
NERKGGRSRS
320
HTRSKSRSSS
330
KSRSRRKRSQ
340
SKHRSRSHNR
350
SRSRQKDRRR
360
SKSPHKKRSK
370
SRERRKSRSR
380
SRSRDKRKDT
390
REKIKEKERV
400
KEKDREKERE
410
KERDREKERE
420
KEKERGKNKD
430
KDRDKEREKD
440
RDKDKEKDRD
450
REREKEHEKE
460
RDKEKEKEQD
470
KEKEREKDRS
480
KEIDEKRKKD
490
KKSRTPPRSY
500
NASRRSRSSS
510
RERRRRRSRS
520
SSRSPRTSKT
530
IKRKSSRSPS
540
PRSRNKKDKK
550
REKERDHISE
560
RRERERSTST
570
RKSSNDRDGK
580
EKAEKNSTSL
590
KEKEHNKEPD
600
SNVGKEVDDK
610
DPPPRTEENK
620
VQQNGNCQPN
630
EENLSTKTEA
V
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.