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Overview

Uniprot IDA0A287B8B1
Protein Name-
Gene NameST13
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
14 SELRAFVKMCKQDPS
153 RLAILYAKRASVFIK
186 PDSAQPYKWRGKAHR

Function

One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins

Protein Sequence

10 MDPRKVSELR 20 AFVKMCKQDP 30 SVLHTEEMRF 40 LREWVESMGG 50 KIPPATHKTK 60 SEENTKEEKT 70 DSKKVEENIK 80 TDEPSSEESD 90 LEIDNEGVIE 100 PDTDAPQEMG 110 DENVEITEEM 120 MDQANDKKVA 130 AIDALNNGEL 140 QKAIDLFTDA 150 IKLNPRLAIL 160 YAKRASVFIK 170 LQKPNAAIRD 180 CDRAIEINPD 190 SAQPYKWRGK 200 AHRLLGHWEE 210 AAHDLALACK 220 LDYDEDASAM 230 LKEVQPRAQK 240 IAEHRRKYER 250 KREEREIKER 260 IERVKKAREE 270 HERAQREEEA 280 RRQSGAQYGS 290 FPGNFPGGMP 300 GMGGSMPGMA 310 GMPGLNEILS 320 DPEVLAAMQD 330 PEVMVAFQDV 340 AQNPANMSKY 350 QSNPKVMNLI 360 SKLSAKFGGQ A

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Molecular Function GO:0046983 protein dimerization activity

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.