Search Results

Overview

Uniprot ID	A0A287B906
Protein Name	Nexilin
Gene Name	NEXN
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
102	PKLTGTVKGKFAEME
186	KTSGKIKKNFEDLEK
435	REYEELIKLKRSGSI
453	NLKSKFEKIGQLSEK
659	MCKAVNNKGSAASTC

Function

Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity

Protein Sequence

10 MNDISQKAEI 20 LLSSSKPVPK 30 SYVPKLGKGD 40 VKDKFEAMQR 50 AREERNQRRS 60 RDEKQRRKEQ 70 YIREREWNRR 80 KQEIKEMLAS 90 DEEEVSSKIE 100 KAYVPKLTGT 110 VKGKFAEMEK 120 QRQEEQRKRT 130 EEERKRRIEQ 140 DMLEKRKIQR 150 ELAKRAEQIE 160 DINNTGTESA 170 SEEGDDSLLV 180 TVVPVKSHKT 190 SGKIKKNFED 200 LEKEREEKER 210 VKYEEDKRIR 220 YEEQRRSLKE 230 AKCLSLVMDD 240 ELENEAKKES 250 FSPGKLKLTF 260 EELERQRQEN 270 RRKQAEEEAR 280 KRLEEERRGF 290 EEARRQMVNE 300 EEENQDTENI 310 FKAYRPGKLK 320 LSFEEIERQR 330 REDEKRKAEE 340 EARRRIEEEK 350 KAFAEARRSM 360 AVDDDSPEMY 370 KTISQESLTP 380 GKLEINFEEL 390 LKQKMEEERR 400 RTEEERKHKL 410 EMEKQEFEQL 420 RQEMGEEEEE 430 NETFELSREY 440 EELIKLKRSG 450 SIQAKNLKSK 460 FEKIGQLSEK 470 EIQKKIEEER 480 ARRRAIDLEI 490 KEREAENFHE 500 EEDVDVKPAK 510 KSEAPFTHKV 520 NMKARFERMA 530 KAREEEEQRR 540 IEEQKLLRMQ 550 FEQKEIDAAL 560 QKKREEEEEE 570 EGSTMNGSTI 580 EDEEETRSGA 590 PWFKKPLKNT 600 SVVDSEPVRF 610 TVKVTGEPKP 620 EITWWFEGEL 630 LQDGEDYQYI 640 ERGETYCLYL 650 PETFPEDEGE 660 YMCKAVNNKG 670 SAASTCILTI ESKN

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005912	adherens junction
Cellular Component	GO:0030424	axon
Cellular Component	GO:0005856	cytoskeleton
Cellular Component	GO:0005925	focal adhesion
Cellular Component	GO:0005886	plasma membrane
Cellular Component	GO:0030018	Z disc
Molecular Function	GO:0003779	actin binding
Molecular Function	GO:0098632	cell-cell adhesion mediator activity
Biological Process	GO:0007411	axon guidance
Biological Process	GO:0070593	dendrite self-avoidance
Biological Process	GO:0007156	homophilic cell-cell adhesion

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.