Search Results
Overview
| Uniprot ID | A0A287B982 |
|---|---|
| Protein Name | Phosphatidylinositol-glycan biosynthesis class X protein |
| Gene Name | PIGX |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 70 | RDLLIRVKFGEGIED |
Function
Stabilizing subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM
Protein Sequence
10
FCLFAFSRGS
20
NRSCSRWSTP
30
QPQQLGILCL
40
FYFKKNLLVL
50
LGIRATCSEI
60
ILKQEVLKDG
70
FHRDLLIRVK
80
FGEGIEDLQT
90
CRVLIRQYIP
100
TGLFVDPYEL
110
ASLREKNITE
120
AVMVSENFNI
130
EAPDYLSKES
140
EVLIYARQDP
150
QCTDCFQAFL
160
PVHYRYHRPH
170
CNDEETFIVV
180
NNPDLLMYCD
190
QEFPVLKCWT
200
QSEMTAPCAL
210
NSQDICQWNN
220
MKYKSVYKNV
230
TLLVPVGLTI
240
HTSLVCSVTL
250
LVTVLCSALI
260
LVAVFTYGHF
SL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Biological Process | GO:0006506 | GPI anchor biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.