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Overview

Uniprot IDA0A287BA12
Protein Namevesicle-fusing ATPase
Gene NameVPS4B
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
355 ALMQPVRKVQSATHF
61 AKQNIRAKCTEYLDR

Function

No function data available.

Protein Sequence

10 MASTSPNLQK 20 AIDLASKAAQ 30 EDKAGNYEEA 40 LQFYQHAVQY 50 FLHIIKYEAQ 60 GDKAKQNIRA 70 KCTEYLDRAE 80 KLKEYLKKKE 90 SKPQKPVKEG 100 QPSPADEKGN 110 DSDGEGESDD 120 PEKKKLQNQL 130 QGAIVIERPN 140 VKWSDVAGLE 150 GAKEALKEAI 160 ILPIKFPHLF 170 TGKRTPWRGI 180 LLFGPPGTGK 190 SYLAKAVATE 200 ANNSTFFSVS 210 SSDLVSKWLG 220 ESEKLVKNLF 230 QLARENKPSI 240 IFIDEIDSLC 250 GSRSENESEA 260 ARRIKTEFLV 270 QMQGVGVDND 280 GILVLGATNI 290 PWVLDSAIRR 300 RFEKRIYIPL 310 PEAHTRTAMF 320 KLHLGTTQNN 330 LTEADFWDLG 340 KKTEGYSGAD 350 ISIIVRDALM 360 QPVRKVQSAT 370 HFKKVRGPSR 380 ADPNHIVDDL 390 LTPCSPGDPG 400 AIEMTWMDIP 410 GDKLLEPVVC 420 MSDMLRSLSS 430 TKPTVNEHDL 440 LKLKKFTEDF GQEG

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005813 centrosome
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005768 endosome
Cellular Component GO:0090543 Flemming body
Cellular Component GO:0031902 late endosome membrane
Cellular Component GO:0005634 nucleus
Cellular Component GO:0000922 spindle pole
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016887 ATP hydrolysis activity
Molecular Function GO:0042803 protein homodimerization activity
Molecular Function GO:0044877 protein-containing complex binding
Biological Process GO:0016197 endosomal transport
Biological Process GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway
Biological Process GO:1904903 ESCRT III complex disassembly
Biological Process GO:0061738 late endosomal microautophagy
Biological Process GO:0061952 midbody abscission
Biological Process GO:0007080 mitotic metaphase chromosome alignment
Biological Process GO:0036258 multivesicular body assembly
Biological Process GO:1903542 negative regulation of exosomal secretion
Biological Process GO:0006997 nucleus organization
Biological Process GO:1903724 positive regulation of centriole elongation
Biological Process GO:1903543 positive regulation of exosomal secretion
Biological Process GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
Biological Process GO:0051261 protein depolymerization
Biological Process GO:0015031 protein transport
Biological Process GO:1901673 regulation of mitotic spindle assembly
Biological Process GO:0033993 response to lipid
Biological Process GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Biological Process GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
Biological Process GO:0007033 vacuole organization
Biological Process GO:0046761 viral budding from plasma membrane
Biological Process GO:0039702 viral budding via host ESCRT complex

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.