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Overview

Uniprot ID	A0A287BAF6
Protein Name	Transducin beta-like protein 3
Gene Name	TBL3
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
678	RDPESCEKLEATVLQ

Function

Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Protein Sequence

10 MASRGCKVSP 20 GLRPFCHQLD 30 QTGQHLFCVC 40 GTRVNILDVA 50 SGAVLRSLEQ 60 EDQEDITAFD 70 LSPDDEVLVT 80 ATRALLLAQW 90 AWREGSIVRL 100 WKAIHTAPVA 110 AMAFDPTSTL 120 LATGGCDGAV 130 RVWDVVRHYG 140 THHFRGSPGV 150 VHLVAFHPDP 160 ARLLLFSSAA 170 DASIRVWSLQ 180 DRSCLAVLTA 190 HYSAVTSVTF 200 SADGYTMISS 210 GRDKICTVWD 220 LQSLQATKTV 230 PVFESVEAAV 240 LLPEEPAPEL 250 GVKSTGLHFL 260 TAGDQGILRV 270 WEAASGQCVH 280 AQPRLPGPGQ 290 ELTHCALARA 300 AGLLLSVTAD 310 HNLLLYEARS 320 LQLQKQFAGY 330 SEEVLDVRFL 340 GPENSHVVVA 350 SNSPCLKVFE 360 LQTSACQILH 370 GHTDIVLALD 380 VFRKGWLFAS 390 CAKDQSIRIW 400 RINKAGLVAC 410 VAQGSGHTHS 420 VGTICCSRLK 430 ESFLVTGSQD 440 CTVKLWPLPE 450 ALPSRSTAPD 460 SGPVLLQAQA 470 TQRCHDKDIN 480 SVAIAPNDKL 490 LATGSQDRTA 500 KLWALPQCQL 510 LGIFSGHRRG 520 LWCVQFSPMD 530 QVLATASADG 540 TVKLWALQDF 550 SCLKTFEGHD 560 ASVGASRCRP 570 SGSDGLVKLW 580 TIKSNECVRT 590 LDAHEDKVWG 600 LHCSRLDDRA 610 LTAASDSRVI 620 LWKDVTEEEQ 630 AEEEARREEE 640 VVRQQELDNL 650 LHEKRYLRAL 660 GLAISLDRPH 670 TVLTVIQAIR 680 RDPESCEKLE 690 ATVLQLRRDQ 700 KEALLRFCVT 710 WNTNSRHCHE 720 AQAVLGMLLR 730 HEAPEELLAY 740 DGVRASLEAL 750 LPYTERHFQR 760 LSRTLQAAAF 770 LDFLWHSMKL 780 PTLPAAPPAL

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0032040	small-subunit processome
Biological Process	GO:0006364	rRNA processing

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.