Search Results
Overview
| Uniprot ID | A0A287BDT8 |
|---|---|
| Protein Name | Glycerol-3-phosphate phosphatase |
| Gene Name | PGP |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 80 | TREAYAEKLQRLGFG |
Function
Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear. In vitro, also has a phosphatase activity toward ADP, ATP, GDP and GTP
Protein Sequence
10
MAATEASGDD
20
VRCVRLSAER
30
ARTLLADVDT
40
LLFDCDGVLW
50
RGETAVPGAP
60
EALTALRARG
70
KRLGFITNNS
80
SKTREAYAEK
90
LQRLGFGGPS
100
GPNAGREIFG
110
TAYCTALYLR
120
QRLGGAPTPK
130
AYVLGSAALA
140
AELEAVGVTC
150
VGVGPEPLQG
160
EGPSAWLDAP
170
LEPDVRAVVV
180
GFDPHFSYMK
190
LTKAVRYLQQ
200
PSCLLVGTNM
210
DNRLPLENGR
220
FIAGTGCLVR
230
AVEMAAQRQA
240
DIIGKPSRFI
250
FDCVSQEYGI
260
NPERTVMVGD
270
RLDTDILLGV
280
TCGLKTVLTL
290
TGVSTLGDVK
300
SNQESDCMSR
310
KKMVPDFYVD
320
SIADLLPALQ
G
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004725 | protein tyrosine phosphatase activity |
| Molecular Function | GO:0043136 | sn-glycerol 3-phosphatase activity |
| Biological Process | GO:0006114 | glycerol biosynthetic process |
| Biological Process | GO:0006650 | glycerophospholipid metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.