Search Results
Overview
| Uniprot ID | A0A287BED1 |
|---|---|
| Protein Name | Prefoldin subunit 1 |
| Gene Name | PFDN1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 11 | PVDLELKKAFTELQA |
| 28 | IDTQQKVKLADIQIE |
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins
Protein Sequence
10
MAAPVDLELK
20
KAFTELQAKV
30
IDTQQKVKLA
40
DIQIEQLNRT
50
KKHAHLTDTE
60
IMTLVDETNM
70
YEGVGRMFIL
80
QSKEAIHNQL
90
LEKQKIAEEK
100
IKELEQKKSY
110
LERSVKEAED
120
NIREMLMARR
AQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016272 | prefoldin complex |
| Molecular Function | GO:0001540 | amyloid-beta binding |
| Molecular Function | GO:0044183 | protein folding chaperone |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:1905907 | negative regulation of amyloid fibril formation |
| Biological Process | GO:0006457 | protein folding |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.