Search Results
Overview
| Uniprot ID | A0A287BEJ2 |
|---|---|
| Protein Name | BRISC and BRCA1-A complex member 2 |
| Gene Name | BABAM2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 57 | GPNCDRFKLHIPYAG |
Function
May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway
Protein Sequence
10
MSPEVALNRI
20
SPMLSPFISS
30
VVRNGKVGLD
40
ATNCLRITDL
50
KSGCTSLTPG
60
PNCDRFKLHI
70
PYAGETLKWD
80
IIFNAQYPEL
90
PPDFIFGEDA
100
EFLPDPSALH
110
NLASWNPSNP
120
ECLLLVVKEL
130
VQQYHQFQCS
140
RLRESSRLMF
150
EYQTLLEEPQ
160
YGENMEIYAG
170
KKNNWTGEFS
180
ARFLLKLPVD
190
FSNIPTYLLK
200
DVNEDPGEDV
210
ALLSVSFEDT
220
EATQVYPKLY
230
LSPRIEHALG
240
GSSALHIPAF
250
PGGGCLIDYV
260
PQVCHLLTNK
270
VQYVIQGYHK
280
RREYIAAFLS
290
HFGTGVVEYD
300
AEGFTKLTLL
310
LMWKDFCFLV
320
HIDLPLFFPR
330
DQPTLTFQSV
340
YHFTNSGQLY
350
SQAQKNYPYS
360
PRWDGNEMAK
370
RAKAYFKTFV
380
PQFQEAAFAN
GKL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0070531 | BRCA1-A complex |
| Cellular Component | GO:0070552 | BRISC complex |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0000152 | nuclear ubiquitin ligase complex |
| Molecular Function | GO:0031593 | polyubiquitin modification-dependent protein binding |
| Molecular Function | GO:0005164 | tumor necrosis factor receptor binding |
| Biological Process | GO:0006915 | apoptotic process |
| Biological Process | GO:0051301 | cell division |
| Biological Process | GO:0071479 | cellular response to ionizing radiation |
| Biological Process | GO:0006325 | chromatin organization |
| Biological Process | GO:0006302 | double-strand break repair |
| Biological Process | GO:0007095 | mitotic G2 DNA damage checkpoint signaling |
| Biological Process | GO:0043066 | negative regulation of apoptotic process |
| Biological Process | GO:0045739 | positive regulation of DNA repair |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.