Search Results
Overview
| Uniprot ID | A0A287BG40 |
|---|---|
| Protein Name | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial |
| Gene Name | NDUFV2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 154 | SILEAIQKKLGIKVG |
Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Parts of the peripheral arm of the enzyme, where the electrons from NADH are accepted by flavin mononucleotide (FMN) and then passed along a chain of iron-sulfur clusters by electron tunnelling to the final acceptor ubiquinone. Contains one iron-sulfur cluster
Protein Sequence
10
MFLTAALRAR
20
ATGFTAQWGR
30
HVRNLHKTAV
40
QNGAGGALFV
50
HRDTPENNPD
60
TPFDFTPENY
70
KRIEAIVKNY
80
PEGHKAAAVL
90
PVLDLAQRQN
100
GWLPISAMNK
110
VAEILQVPPM
120
RVYEVATFYT
130
MYNRKPVGKY
140
HIQVCTTTPC
150
MLRNSDSILE
160
AIQKKLGIKV
170
GETTPDKLFT
180
LIEVECLGAC
190
VNAPMVQIND
200
NYYEDLTPKD
210
IEEIIDELKA
220
GKIPKPGPRS
230
GRFSCEPAGG
240
LTSLTEPPKG
PGFGVQAGL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0045271 | respiratory chain complex I |
| Molecular Function | GO:0051537 | 2 iron, 2 sulfur cluster binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0008137 | NADH dehydrogenase (ubiquinone) activity |
| Molecular Function | GO:0016491 | oxidoreductase activity |
| Biological Process | GO:0048738 | cardiac muscle tissue development |
| Biological Process | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone |
| Biological Process | GO:0007399 | nervous system development |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.