Search Results

Overview

Uniprot ID	A0A287BGB1
Protein Name	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
Gene Name	PPP2R5D
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
114	SKNRELQKLPALKDS
133	REELFIQKLRQCCVL
501	DDCTQQYKAEKQKGR
584	EKVLLRRKSELPQDV
595	PQDVYTIKALEAHKR
83	PPPTQLSKIKYSGGP
85	PTQLSKIKYSGGPQI

Function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment

Protein Sequence

10 MRPRPLPSPA 20 SANSTSILSL 30 QEPPKLAKST 40 AKPSSSSKDG 50 AGESAEEAQP 60 QPQPQPQPPP 70 QPQPPSSNKR 80 PSNSTPPPTQ 90 LSKIKYSGGP 100 QIVKKERRQS 110 SSRFNLSKNR 120 ELQKLPALKD 130 SPTQEREELF 140 IQKLRQCCVL 150 FDFVSDPLSD 160 LKFKEVKRAG 170 LNEMVEYITH 180 SRDVVTEAIY 190 PEAVTMFSVN 200 LFRTLPPSSN 210 PTGAEFDPEE 220 DEPTLEAAWP 230 HLQLVYEFFL 240 RFLESPDFQP 250 NIAKKYIDQK 260 FVLALLDLFD 270 SEDPRERDFL 280 KTILHRIYGK 290 FLGLRAYIRR 300 QINHIFYRFI 310 YETEHHNGIA 320 ELLEILGSII 330 NGFALPLKEE 340 HKMFLIRVLL 350 PLHKVKSLSV 360 YHPQLAYCVV 370 QFLEKESSLT 380 EPVIVGLLKF 390 WPKTHSPKEV 400 MFLNELEEIL 410 DVIEPSEFSK 420 VMEPLFRQLA 430 KCVSSPHFQV 440 AERALYYWNN 450 EYIMSLISDN 460 AARVLPIMFP 470 ALYRNSKSHW 480 NKTIHGLIYN 490 ALKLFMEMNQ 500 KLFDDCTQQY 510 KAEKQKGRFR 520 MKEREEMWQK 530 IEELARLNPQ 540 YPMFRAPPPL 550 PPVYSMETET 560 PTAEDIQLLK 570 RTVETEAVQM 580 LKDIKKEKVL 590 LRRKSELPQD 600 VYTIKALEAH 610 KRAEEFLTAS QEAL

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0005654	nucleoplasm
Cellular Component	GO:0000159	protein phosphatase type 2A complex
Molecular Function	GO:0072542	protein phosphatase activator activity
Biological Process	GO:0007165	signal transduction

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.