Search Results
Overview
| Uniprot ID | A0A287BHL2 |
|---|---|
| Protein Name | Glycerol-3-phosphate phosphatase |
| Gene Name | PGP |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 93 | TREAYAEKLQRLGFG |
Function
Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear. In vitro, also has a phosphatase activity toward ADP, ATP, GDP and GTP
Protein Sequence
10
MSAPGAGRAR
20
RRAAARTSGC
30
RRRRRRRRRR
40
RRRPVVAGAG
50
GHGGDGGQRR
60
RRPLRAAERR
70
AGPDAAGRRG
80
HAAVRLRRRA
90
VARSKTREAY
100
AEKLQRLGFG
110
GPSGPNAGRE
120
IFGTAYCTAL
130
YLRQRLGGAP
140
TPKAYVLGSA
150
ALAAELEAVG
160
VTCVGVGPEP
170
LQGEGPSAWL
180
DAPLEPDVRA
190
VVVGFDPHFS
200
YMKLTKAVRY
210
LQQPSCLLVG
220
TNMDNRLPLE
230
NGRFIAGTGC
240
LVRAVEMAAQ
250
RQADIIGKPS
260
RFIFDCVSQE
270
YGINPERTVM
280
VGDRLDTDIL
290
LGVTCGLKTV
300
LTLTGVSTLG
310
DVKSNQESDC
320
MSRKKMVPDF
330
YVDSIADLLP
ALQG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0043262 | ADP phosphatase activity |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0008967 | phosphoglycolate phosphatase activity |
| Molecular Function | GO:0004725 | protein tyrosine phosphatase activity |
| Molecular Function | GO:0043136 | sn-glycerol 3-phosphatase activity |
| Biological Process | GO:0006114 | glycerol biosynthetic process |
| Biological Process | GO:0006650 | glycerophospholipid metabolic process |
| Biological Process | GO:0045721 | negative regulation of gluconeogenesis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.