Search Results
Overview
| Uniprot ID | A0A287BJD1 |
|---|---|
| Protein Name | Rab GDP dissociation inhibitor |
| Gene Name | GDI1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 226 | VEGSFVYKGGKIYKV |
| 383 | NGKVVGVKSEGEVAR |
| 392 | EGEVARCKQLICDPS |
| 407 | YVPDRVRKAGQVIRI |
Function
Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP
Protein Sequence
10
MLSSLFTFLP
20
SKVMRGSHGQ
30
MKCPPLHFQP
40
GDQPGMEGAV
50
RRGQGPSRFA
60
VSALGWRARQ
70
GCLGDREVGG
80
QWTLLLAQEC
90
ILSGIMSVNG
100
KKVLHMDRNP
110
YYGGESSSIT
120
PLEELYKRFQ
130
LLEGPPEAMG
140
RGRDWNVDLI
150
PKFLMANGEG
160
DKGGVMAGVG
170
VGLWGQLAGG
180
HTPETGPPDQ
190
LELLQGAALT
200
VAFPAPAAGQ
210
LVKMLLYTEV
220
TRYLDFKVVE
230
GSFVYKGGKI
240
YKVPSTETEA
250
LASNLMGMFE
260
KRRFRKFLVF
270
VANFDENDPK
280
TFEGVDPQST
290
SMRDVYRKFD
300
LGQDVIDFTG
310
HALALYRTDD
320
YLDQPCLETI
330
NRIKLYSESL
340
ARYGKSPYLY
350
PLYGLGELPQ
360
GFARLSAIYG
370
GTYMLNKPVD
380
DIIMENGKVV
390
GVKSEGEVAR
400
CKQLICDPSY
410
VPDRVRKAGQ
420
VIRIICILSH
430
PIKNTNDANS
440
CQIIIPQNQV
450
NRKSDIYVCM
460
ISYAHNVAAQ
470
GKYIAIASTT
480
VETAEPEKEV
490
EPALELLEPI
500
DQKFVAISDL
510
YEPVDDGSES
520
QVFCSCSYDA
530
TTHFETTCND
540
IKDIYKRMVG
550
SAFDFENMKR
560
KQNDVFGEAD
Q
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0030496 | midbody |
| Molecular Function | GO:0005096 | GTPase activator activity |
| Molecular Function | GO:0005093 | Rab GDP-dissociation inhibitor activity |
| Biological Process | GO:0090315 | negative regulation of protein targeting to membrane |
| Biological Process | GO:0034123 | positive regulation of toll-like receptor signaling pathway |
| Biological Process | GO:0015031 | protein transport |
| Biological Process | GO:0007264 | small GTPase-mediated signal transduction |
| Biological Process | GO:0016192 | vesicle-mediated transport |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.