Search Results
Overview
| Uniprot ID | A0A287BKF1 |
|---|---|
| Protein Name | Interferon-induced, double-stranded RNA-activated protein kinase |
| Gene Name | EIF2AK2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 120 | RINTISQKKNLSVNY |
| 149 | YKCKIGRKVYGSGVG |
| 20 | ELNKYQQKNDVILKY |
| 26 | QKNDVILKYRELCKT |
| 309 | TYVIKRVKYDCEKVE |
| 320 | EKVEREVKALATLKH |
Function
No function data available.
Protein Sequence
10
MASGRSPCFY
20
IEELNKYQQK
30
NDVILKYREL
40
CKTGPAHNLR
50
SVAIKKKKRF
60
TYQVVIDEKE
70
FPKAEGRSKK
80
EAKNAAAKLA
90
FEIINKEHKA
100
NSSSSLPTAN
110
PPDRQLTENY
120
IGRINTISQK
130
KNLSVNYEPC
140
EPGEDGPEKF
150
HYKCKIGRKV
160
YGSGVGSTKQ
170
EAKQLAAKQA
180
YEKLQSENFM
190
NADPPSSSCL
200
STASSDIQSS
210
SPTTSTSASE
220
SATENGFSAN
230
TSESSDNSDR
240
LNNSVLSPVN
250
SSGSHPQRVQ
260
RILAPTFTSP
270
MKEENKHSLN
280
PRFVEDFIQI
290
EPIGSGGFGQ
300
VFKAKHKIDK
310
KTYVIKRVKY
320
DCEKVEREVK
330
ALATLKHPNI
340
VLYYGCWDGN
350
DYDPEQSMNT
360
LRSKTRCLFI
370
QMEYCDKGTL
380
EQWIDSQRNK
390
EPDKCLALEF
400
FEQITTGVHY
410
IHSKQLIHRD
420
LKPGNIFLVD
430
TNQIKIGDFG
440
LVTSLKNDEK
450
RTSRKGTLRY
460
MSPEQSSSED
470
YGNEVDIYAL
480
GLILAELLHI
490
CRTFSETLKL
500
FECLKAGVLD
510
VFNYKEKGLL
520
RKLLSNDPKK
530
RPNASEILKT
540
LKEWKNVTEK
KKRNTC
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0003725 | double-stranded RNA binding |
| Molecular Function | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0004715 | non-membrane spanning protein tyrosine kinase activity |
| Biological Process | GO:0140374 | antiviral innate immune response |
| Biological Process | GO:0034198 | cellular response to amino acid starvation |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:2000766 | negative regulation of cytoplasmic translation |
| Biological Process | GO:0033689 | negative regulation of osteoblast proliferation |
| Biological Process | GO:0017148 | negative regulation of translation |
| Biological Process | GO:0045071 | negative regulation of viral genome replication |
| Biological Process | GO:0043123 | positive regulation of canonical NF-kappaB signal transduction |
| Biological Process | GO:0032722 | positive regulation of chemokine production |
| Biological Process | GO:1901224 | positive regulation of non-canonical NF-kappaB signal transduction |
| Biological Process | GO:0032874 | positive regulation of stress-activated MAPK cascade |
| Biological Process | GO:1902036 | regulation of hematopoietic stem cell differentiation |
| Biological Process | GO:1902033 | regulation of hematopoietic stem cell proliferation |
| Biological Process | GO:1900225 | regulation of NLRP3 inflammasome complex assembly |
| Biological Process | GO:0006446 | regulation of translational initiation |
| Biological Process | GO:0035455 | response to interferon-alpha |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.