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Overview

Uniprot IDA0A287BM02
Protein NameHistone PARylation factor 1
Gene NameHPF1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
27 PVDVKKSKSCEADIP

Function

No function data available.

Protein Sequence

10 MVGSGRKRRP 20 GGEGSQCEKP 30 VDVKKSKSCE 40 ADIPTDLRKE 50 VESHYRLSLP 60 EDFYHFWKFC 70 EELDPEKPAD 80 SLSLSLGLRL 90 VGPYDILAGK 100 HKMKKRSASL 110 NCNLHWRFYY 120 DPPEFQTIII 130 GDSKTQFHMG 140 YFRDSPDELP 150 VFVGTNEAKK 160 NCVIVPNGDN 170 VFAAVKLFLM 180 KKLKEVTDKK 190 KISLLKNIDE 200 KLTEAARELG 210 FSLEQRTAKM 220 KQRDKKVVTK 230 TFHGAGLVVP 240 VDKNDVGYRE 250 LPETDANLRR 260 ICKTIAEAPG 270 DDERLKAFAP 280 IQEMMTYVQF 290 ANDECDYGMG 300 LELGTDLFCH 310 GSHYFHKVAG 320 QLLPLAYNLL 330 KRNLFAEIIE 340 GHLADRRRED VDQLAV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000785 chromatin
Cellular Component GO:0005634 nucleus
Cellular Component GO:0090734 site of DNA damage
Molecular Function GO:0003682 chromatin binding
Molecular Function GO:0042393 histone binding
Molecular Function GO:0072572 poly-ADP-D-ribose binding
Molecular Function GO:0140768 protein ADP-ribosyltransferase-substrate adaptor activity
Biological Process GO:0140861 DNA repair-dependent chromatin remodeling
Biological Process GO:0006302 double-strand break repair

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.