Search Results
Overview
| Uniprot ID | A0A287BNK0 |
|---|---|
| Protein Name | Squalene monooxygenase |
| Gene Name | SQLE |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 357 | AAILQAKKSFYWTRK |
Function
Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis
Protein Sequence
10
MLGKKGSNIS
20
ETTLVGAAAS
30
PLISSQNDPE
40
IIIVGSGVLG
50
SALAAVLSRD
60
GRKVTVIERD
70
LKEPDRILGE
80
YLQPGGCHVL
90
KDLGLEDTME
100
GIDAQVVDGY
110
IIHDQESKSE
120
VQIPFPLSEN
130
NHVQSGRAFR
140
HGRFIMGLRK
150
AAMAEPNAKF
160
IEGTVLQLLE
170
EEDVVLGVQY
180
RDKETGDIKE
190
LHAPLTIVAD
200
GLFSKFRKNL
210
ISNKVSVSSH
220
FVGFLMENAP
230
QFKANHAELV
240
LANPSPVLIY
250
QISPSETRVL
260
VDIRGEMPRN
270
LREYMIENIY
280
PQLPDHLKEP
290
FLEASQNSHL
300
RSMPASFLPS
310
SPVNKRGVLL
320
LGDAHNMRHP
330
LTGGGMTVAF
340
NDIKLWRKLL
350
KGIPDLYDDA
360
AILQAKKSFY
370
WTRKMSHSFV
380
VNVLAQALYE
390
LFSATDDSLY
400
QLRKACFFYF
410
KLGGECISGP
420
VALISVLSPN
430
PLVLIGHFFA
440
VAVYATYFCF
450
KSEPWITKPR
460
AIFSSGAVLY
470
RACSVLFPLI
YSEIKYLVH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Molecular Function | GO:0050660 | flavin adenine dinucleotide binding |
| Molecular Function | GO:0004506 | squalene monooxygenase activity |
| Biological Process | GO:0016126 | sterol biosynthetic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.