Search Results
Overview
| Uniprot ID | A0A287BNZ5 |
|---|---|
| Protein Name | Mannose-6-phosphate isomerase |
| Gene Name | MPI |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 204 | ECLGSKVKDTFSGKL |
Function
Isomerase that catalyzes the interconversion of fructose-6-P and mannose-6-P and has a critical role in the supply of D-mannose derivatives required for many eukaryotic glycosylation reactions
Protein Sequence
10
MDGCRVEEGA
20
LQVGTEPLLQ
30
PYKESLQGRG
40
LRVGHFKSGC
50
SGRDSSHSLS
60
VTSAQQPHIS
70
KRSLLPVLHI
80
RTVRPAKVPQ
90
QPTNPLFDSI
100
PQTKPSARSS
110
FPETGGSGLR
120
NGVEADVQSV
130
SPVFPLSCVV
140
QQYAWGKMGS
150
NSEVARLLAS
160
SDALAQISED
170
KPYAELWMGT
180
HPRGDSKILD
190
NRISQKTLGQ
200
WIAENQECLG
210
SKVKDTFSGK
220
LPFLFKVLSV
230
ETALSIQAHP
240
NKELAEKLHL
250
QAPQHYPDAN
260
HKPEIAIALT
270
SFQGLCGFRP
280
VEEIVTFLTK
290
VPEFQFLIGD
300
SAATQLKQSI
310
SHDSQAVASA
320
LRSCFSHLMN
330
SEKKVVVEQL
340
NLLVKRISQQ
350
VAAGNNMEDI
360
CGELLLQLHQ
370
QYPGDIGCFA
380
IYFLNLLTLK
390
PGEAMFLEAN
400
VPHAYLKGDC
410
VECMACSDNT
420
VRAGLTPKFI
430
DVSTLCEMLS
440
YTPSPSQDRL
450
FPPTQSQEDP
460
YLVIYDPPVP
470
DFTVMKMEVP
480
GSVPEYKVLA
490
LDSASILLMV
500
QGTVTASTPT
510
AQATIPLQRG
520
GVLFIGANES
530
VSLKLTMPED
540
LLMFRACCLL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0004476 | mannose-6-phosphate isomerase activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0061729 | GDP-D-mannose biosynthetic process from fructose-6-phosphate |
| Biological Process | GO:0009298 | GDP-mannose biosynthetic process |
| Biological Process | GO:0061611 | mannose to fructose-6-phosphate catabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.