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Overview

Uniprot IDA0A287BPP9
Protein NameProteasome subunit beta
Gene NamePSMB1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
204 DRAMRLVKDVFISAA
73 RDSPKCYKLTDKTVI
77 KCYKLTDKTVIGCSG

Function

Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity

Protein Sequence

10 MLSSVAAYSV 20 PGRDLAMDPH 30 SAAGPSQLRF 40 SPYAFNGGTV 50 LAIAGEDFSI 60 VASDTRLSEG 70 FSIHTRDSPK 80 CYKLTDKTVI 90 GCSGFHGDCL 100 TLTKIIEARL 110 KMYKHSNNKA 120 MTTGAIAAML 130 STILYSRRFF 140 PYYVYNIIGG 150 LDEEGKGAVY 160 SFDPVGSYQR 170 DSFKAGGSAS 180 AMLQPLLDNQ 190 VGFKNMQNVE 200 HVPLSLDRAM 210 RLVKDVFISA 220 AERDVYTGDA 230 LRICIVTKEG 240 VREETVPLRK D

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005839 proteasome core complex
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process GO:0051603 proteolysis involved in protein catabolic process
Biological Process GO:0061136 regulation of proteasomal protein catabolic process
Biological Process GO:0006979 response to oxidative stress

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.