Search Results

Overview

Uniprot IDA0A287BQI7
Protein NameExocyst complex component 7
Gene NameEXOC7
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
201 SPELNKVKLLFERGK
681 EELCKIQKAWAIPDT

Function

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. It is required for neuron survival and plays an essential role in cortical development

Protein Sequence

10 MATPDRCTEF 20 YAGALPPATP 30 NMAPLARPGA 40 GPRAEVGVTG 50 TGAERVSWDE 60 VLGSGSRRVE 70 AMIPPQEASA 80 RRREIEDKLK 90 QEEETLSFIR 100 DSLEKSDQLT 110 KNMVSILSSF 120 ESRLMKLENS 130 IIPVHKQTEN 140 LQRLQENVEK 150 TLSCLDHVIS 160 YYHVASDTER 170 IIREGPTGRL 180 EEYLGSMAKI 190 QKAVEYFQDN 200 SPDSPELNKV 210 KLLFERGKES 220 LESEFRSLMT 230 RHSKVVSPVL 240 ILDLISGEDD 250 LEVPDEVPLE 260 HLPESVLQDV 270 IRIARWLVEY 280 GRNQDFMNVY 290 YQIRSSQLDR 300 SIKGLKEHFR 310 KSSSSSGVPY 320 SPAIPNKRKD 330 TPTKKPVKRP 340 GTIRKAQNLL 350 KQYSQHGLDG 360 KKGGSNLIPL 370 EGRDDMLDVE 380 TDAYIHCVSA 390 FVKLAQSEYQ 400 LLTDVIPEHH 410 QKKTFDSLIQ 420 DALDGLMLEG 430 ENIVAAARKA 440 IIRHDFSAVL 450 TVFPILRHLK 460 QTKPEFDQVL 470 QGTAASTKNK 480 LPGLITAMET 490 VGAKALEDFA 500 DNIKNDPDKE 510 YNMPKDGTVH 520 ELTSNAILFL 530 QQLLDFQETA 540 GAMLASQETS 550 SSATSYNSEF 560 SKRLLSTYIC 570 KVLGNLQLNL 580 LSKSKVYEDP 590 ALSAVFLHNN 600 YNYILKALEK 610 SELIQLVAVT 620 QKTAERSYRE 630 HIEQQIQTYQ 640 RSWLKVTDYL 650 TEKNLPVFQP 660 GVKLRDKERQ 670 VIKERFKGFN 680 DGLEELCKIQ 690 KAWAIPDTEQ 700 RDKIRQAQKN 710 IVKETYGAFL 720 HRYGSVPFTK 730 NPEKYIKYRV 740 EQVGDMIDRL FDTSA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0000145 exocyst
Cellular Component GO:0090543 Flemming body
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
Biological Process GO:0006887 exocytosis
Biological Process GO:0015031 protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.