Search Results
Overview
| Uniprot ID | A0A287BRL0 |
|---|---|
| Protein Name | Spliceosome-associated protein CWC15 homolog |
| Gene Name | CWC15 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 220 | WDDDVVFKNCAKGVD |
| 224 | VVFKNCAKGVDDQKK |
Function
Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs
Protein Sequence
10
LEVLEISETS
20
QEPLSNPQIR
30
IVILSSFPNG
40
TLCFRNSGQS
50
CFSQAVFYDY
60
SRVFLRSIFA
70
LVCFCFRQTT
80
QDAPEEVRNR
90
DFRRELEERE
100
RAAAREKNRD
110
RPTREHTTSS
120
SVSKKPRLDQ
130
IPAANLDADD
140
PLTDEEDEDE
150
DFEEESDDDD
160
TAALLAELEK
170
IKKERAEEQA
180
RKEQEQKAEE
190
ERIRMENILS
200
GNPLLNLTGP
210
SQPQSNFKVK
220
RRWDDDVVFK
230
NCAKGVDDQK
240
KDKRFVNDTL
250
RSEFHKKFME
KYIK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0071007 | U2-type catalytic step 2 spliceosome |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0045292 | mRNA cis splicing, via spliceosome |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.