Search Results
Overview
| Uniprot ID | A0A287BRT6 |
|---|---|
| Protein Name | Replication factor C subunit 2 |
| Gene Name | RFC2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 130 | QQKVTLPKGRHKIII |
| 190 | CAVLRYTKLTDAQIL |
| 206 | RLLNVIEKEKVPYTD |
Function
Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA. This subunit binds ATP
Protein Sequence
10
MDAGGSGSGA
20
DERGAQDPAP
30
APSKAPGSAG
40
HYELPWVEKY
50
RPVKLNEIVG
60
NEDTVSRLEV
70
FAREGNVPNI
80
IIAGPPGTGK
90
TTSILCLARA
100
LLGPALKDAV
110
LELNASNDRG
120
IDVVRNKIKM
130
FAQQKVTLPK
140
GRHKIIILDE
150
ADSMTDGAQQ
160
ALRRTMEIYS
170
KTTRFALACN
180
ASDKIIEPIQ
190
SRCAVLRYTK
200
LTDAQILARL
210
LNVIEKEKVP
220
YTDDGLEAII
230
FTAQGDMRQA
240
LNNLQSTFSG
250
FGFINSENVF
260
KVCDEPHPLL
270
VKEMIQHCVS
280
ANIDEAYKIL
290
AHLWHLGYSP
300
EDIIGNIFRV
310
CKTFQMAEYL
320
KLEFIKEIGY
330
THMRVAEGVN
340
SLLQMAGLLA
350
RLCQKTVAPV
AS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0031390 | Ctf18 RFC-like complex |
| Cellular Component | GO:0005663 | DNA replication factor C complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003689 | DNA clamp loader activity |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0017116 | single-stranded DNA helicase activity |
| Biological Process | GO:0006281 | DNA repair |
| Biological Process | GO:0006261 | DNA-templated DNA replication |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.