Search Results

Overview

Uniprot IDA0A287BRW8
Protein NameUbiquitin-like modifier-activating enzyme 6
Gene NameUBA6
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
1358 LTMHKLVKPSTEKKY
639 AVQVKTPKTFCFEPL
696 IGCQQDSKELLKLAT

Function

Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system

Protein Sequence

10 MANSASPEQN 20 QNHCSAINSS 30 ILLTQGNLPT 40 LTLSGKIRVT 50 VTFFLFLLST 60 AFNASFLLKL 70 QKWTQRKEKG 80 KKLSRMKVLL 90 KHLTLANLLE 100 TLIVMPLDGM 110 WNITVQWYAG 120 EFLCKVLSYL 130 KLFSMYAPAF 140 MMVVISLDRS 150 LAITRPLAVK 160 SNSRLGRFMI 170 GLAWLLSSIF 180 AGPQLYIFRM 190 IHLADSSGQT 200 EGFSQCVTHG 210 SFPQWWHQAF 220 YNFFTFSCLF 230 IIPLLIMLIC 240 NAKIMFTLTR 250 VLQQDPHKSS 260 VPGRCHVPSA 270 FRLRLYPPDP 280 SPNSAATATT 290 CSKARPSTTP 300 KPEARTPLGL 310 TGRRRQADLS 320 PPAPSGDVTA 330 RPLTSRPRPL 340 PCLRWSAAAE 350 SQETMEGSQP 360 VATHQGEEAS 370 CSSWGPGSVN 380 TNLPIMPTES 390 VEIDDALYSR 400 QRYVLGDTAM 410 QKMARSHVFL 420 SGMGGLGLEI 430 AKNLVLAGIK 440 AVTIHDTEKC 450 QAWDLGTNFF 460 LCEDDVVNSR 470 NRAEAVLQHI 480 AELNPYVHVT 490 SSSVPLNEST 500 DLSFLDKYQC 510 VVLTEIKLPL 520 RKKINDFCRS 530 QCPPIKFICA 540 DVHGVWSRLF 550 CDFGDEFEVL 560 DTTGEEPKEI 570 FISNITQANP 580 GIVTCLENHP 590 HKLETGQFLT 600 FREINGMTGL 610 NGSTQQITVI 620 SPFSFSIGDT 630 TGLEPYLHGG 640 IAVQVKTPKT 650 FCFEPLEKQI 660 KHPKCLIADF 670 SKPEASLEIH 680 SAMLALDQFQ 690 ENYSRKPNIG 700 CQQDSKELLK 710 LATSICETLE 720 EKPEVNNDIV 730 RWLSWTAQGF 740 LPPLAATVGG 750 LASQEVLKAV 760 TGKFSPLCQW 770 LYIEAADIVE 780 SLDKPEREEF 790 LPRGDRYDAL 800 RACIGDTLCQ 810 KLQNLNIFLV 820 GCGAIGCEML 830 KNFALLGVGT 840 GKEKGMVTVT 850 DPDLIEKSNL 860 NRQFLFRPHH 870 IQKPKSYTAA 880 DATLKINPQL 890 KIDAHLNKVC 900 SATEAIYNDE 910 FYTKQDIIIT 920 ALDNVEARRY 930 VDSRCLANLR 940 PLLDSGTMGT 950 KGHTEVIVPH 960 LTESYNSHRD 970 PPEEEIPFCT 980 LKSFPAAIEH 990 TIQWARDKFE 1000 SSFSYKPSLF 1010 NKFWQTYSSA 1020 EEVLQKIQTG 1030 HSLEGCFQVI 1040 KLLSRRPRNW 1050 TQCVELARLK 1060 FEKYFNHKAL 1070 QLLHCFPLDT 1080 RLKDGSLFWQ 1090 SPKRPPSPLK 1100 FDLNEPLHLS 1110 FLLNAAKLYA 1120 TVYCIPYTEE 1130 DLSADTLLNI 1140 LSEVKIQEFK 1150 PSNKVVQTDE 1160 TARKPDHVPI 1170 SSEDERNAIF 1180 QLEKAISSNE 1190 ATASDLQMAV 1200 LSFEKDDDRN 1210 GHIDFITAAS 1220 NLRAKMYSIE 1230 PADRLKTKRI 1240 AGRIIPAIAT 1250 STAAVSGLVA 1260 LEMIKVAGDY 1270 PFEAYKNCFL 1280 NLAIPIIVFT 1290 ETSEVRKTEI 1300 RNGISFTIWD 1310 RWTIHGKEDF 1320 TLLDFINAVK 1330 EKYGIEPTMV 1340 VQGVKMLYVP 1350 VMPGHAKRLK 1360 LTMHKLVKPS 1370 TEKKYVDLTV 1380 SFAPDTDGDE 1390 DLPGPPVRYY FSHDTD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0016020 membrane
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0019780 FAT10 activating enzyme activity
Molecular Function GO:0004930 G protein-coupled receptor activity
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0016500 protein-hormone receptor activity
Molecular Function GO:0004839 ubiquitin activating enzyme activity
Biological Process GO:0006974 DNA damage response
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.