Search Results
Overview
| Uniprot ID | A0A287BS35 |
|---|---|
| Protein Name | N-acylneuraminate cytidylyltransferase |
| Gene Name | CMAS |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 387 | ISERACSKQTLSSLK |
Function
Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN)
Protein Sequence
10
MPHKGEGRGG
20
GWGREQPLPP
30
HPTPAGGRAG
40
RSGGAELRRR
50
DELPDVEKLG
60
RRRGRKMDSV
70
EKGAATSVSN
80
PRGRPSRGRP
90
PKLQRNSRGG
100
QGRGVEKPPH
110
LAALILARGG
120
SKGIPLKNIK
130
HLAGVPLIGW
140
VLRAALDSGV
150
FQSVWVSTDH
160
DEIENVAKQF
170
GAQVHRRSSE
180
ASKDSSTSLD
190
AIIEFLNYHN
200
EVDIIGNIQA
210
TSPCLHPTDL
220
QKVAEMIREE
230
GYDSVFSVVR
240
RHQFRWGEIQ
250
KGVREMTEPL
260
NLNPAKRPRR
270
QDWDGELYEN
280
GSFYFAKRHL
290
IEMGYLQGGK
300
MAYYEMRAEH
310
SVDIDVDIDW
320
PIAEQRVLRF
330
GYFGKEKLKE
340
IKLFVCNIDG
350
CFTNGHIYVS
360
GDQKEIISYD
370
VKDAIGISLL
380
KKSGIEVRLI
390
SERACSKQTL
400
SSLKLDCKME
410
VNVPDKLAVV
420
DEWRKEMGLC
430
WKEVAYLGNE
440
VSDEECLKKV
450
GLSGVPADAC
460
AAAQKAVGYI
470
CKCNGGRGAL
480
REFAEHIFLL
490
MEKDNERLIA
500
VFLKFLVNAS
510
KNFIKIDFVL
520
YTVKLCVCVL
530
LMMLKLYLFG
540
DSLSGKTCPS
IN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005730 | nucleolus |
| Molecular Function | GO:0008781 | N-acylneuraminate cytidylyltransferase activity |
| Biological Process | GO:0006055 | CMP-N-acetylneuraminate biosynthetic process |
| Biological Process | GO:0006054 | N-acetylneuraminate metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.