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Overview

Uniprot ID	A0A287BSI1
Protein Name	Poly(A) polymerase
Gene Name	PAPOLA
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
635	PSGNAATKIPNPIVG

Function

Polymerase that creates the 3'-poly(A) tail of mRNA's

Protein Sequence

10 MPFPVTTQGS 20 QQTQPPQKHY 30 GITSPISLAA 40 PKETDCLLTQ 50 KLIETLKPFG 60 VFEEEEELQR 70 RILILGKLNN 80 LVKEWIREIS 90 ESKNLPQSVI 100 ENVGGKIFTF 110 GSYRLGVHTK 120 GADIDALCVA 130 PRHVDRSDFF 140 TSFYDKLKLQ 150 EEVKDLRAVE 160 EAFVPVIKLC 170 FDGIEIDILF 180 ARLALQTIPE 190 DLDLRDDSLL 200 KNLDIRCIRS 210 LNGCRVTDEI 220 LHLVPNIDNF 230 RLTLRAIKLW 240 AKRHNIYSNI 250 LGFLGGVSWA 260 MLVARTCQLY 270 PNAIASTLVH 280 KFFLVFSKWE 290 WPNPVLLKQP 300 EECNLNLPVW 310 DPRVNPSDRY 320 HLMPIITPAY 330 PQQNSTYNVS 340 VSTRMVMVEE 350 FKQGLAITDE 360 ILLSKAEWSK 370 LFEAPNFFQK 380 YKHYIVLLAS 390 APTEKQRLEW 400 VGLVESKIRI 410 LVGSLEKNEF 420 ITLAHVNPQS 430 FPAPKENPDK 440 EEFRTMWVIG 450 LVFKKTENSE 460 NLSVDLTYDI 470 QSFTDTVYRQ 480 AINSKMFEVD 490 MKIAAMHVKR 500 KQLHQLLPNH 510 VLQKKKKHST 520 DGVRLTPLND 530 SSLDLSMDSD 540 NSMSVPSPTS 550 AMKTSPLNSS 560 GSSQGRNSPA 570 PAVTAASVTN 580 IQATEVSVPQ 590 VNSSESSGGT 600 SSESIPQTAT 610 QPAISPPPKP 620 TVSRVVSSTR 630 LVNPPPRPSG 640 NAATKIPNPI 650 VGVKRTSSPH 660 KEESPKKTRT 670 EEDETSEDAN 680 CLALSGHDKT 690 EAKEQLDTET 700 STTQSETIQT 710 AASLLASQWT 720 LRAAEELCRR 730 AETAAAGDGA 740 ALMILTLGFT 750 VPSHDHFTTS 760 FCCLLIFIVL SDTNIMVAF

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005654	nucleoplasm
Molecular Function	GO:0005524	ATP binding
Molecular Function	GO:0046872	metal ion binding
Molecular Function	GO:1990817	poly(A) RNA polymerase activity
Molecular Function	GO:0003723	RNA binding
Biological Process	GO:0180010	co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.