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Overview

Uniprot IDA0A287BSM0
Protein NameProtein transport protein Sec31A
Gene NameSEC31A
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
1082 PTEKITKKPIPDEHL
111 SKIIAGDKEVVIAQN
1112 SATDPQTKRKLDDAS
1114 TDPQTKRKLDDASKR
206 RKNEPIIKVSDHSNR
441 VTEQEFLKRSDQLQQ
461 GFVSYCQKKIDASQT
462 FVSYCQKKIDASQTE
489 FEDDSRGKYLELLGY
595 TQKKYFAKSQSKITR
622 IVESCDLKNWREALA
71 SSSHRYHKLIWGPHK
777 PGHQESPKSPYERQQ

Function

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules

Protein Sequence

10 MKLKEVDRTA 20 MQAWSPAQNH 30 PIYLATGTSA 40 QQLDATFSTS 50 ASLEIFELDL 60 SDPSLDMKSC 70 ATFSSSHRYH 80 KLIWGPHKMD 90 SQGNVSGVLI 100 AGGENGNTIL 110 YDPSKIIAGD 120 KEVVIAQNDK 130 HTGPVRALDV 140 NIFQTNLVAS 150 GANESEIYIW 160 DLNNFATPMT 170 PGAKTQPPED 180 ISCIAWNRQV 190 QHILASASPS 200 GRATVWDLRK 210 NEPIIKVSDH 220 SNRMHCSGLA 230 WHPDVATQMV 240 LASEDDRLPV 250 VQMWDLRFAS 260 SPLRVLENHA 270 RGILAIAWSM 280 ADPELLLTCG 290 KDAKILCSNP 300 NTGEVLYELP 310 TNTQWCFDIQ 320 WCPRNPAVLS 330 AASFDGRISV 340 YSIMGGSADG 350 LRQKQVDKLS 360 SSFGNLDPFG 370 TGQPLPPLQI 380 PQQTAQHSVV 390 LPLKKPPKWI 400 RRPVGASFSF 410 GGKLVTFASV 420 RAQPPQGAEP 430 QQPQQHHVLI 440 SQVVTEQEFL 450 KRSDQLQQVV 460 QSQGFVSYCQ 470 KKIDASQTEF 480 EKNVWSFLKV 490 NFEDDSRGKY 500 LELLGYRKED 510 LGKKIALALN 520 KVDGPDVRIK 530 EEKQESEFLP 540 SAGGTFNISV 550 SGDIDGLITQ 560 ALLTGDFESA 570 VDLCLHDNRM 580 ADAIILAIAG 590 GQELLARTQK 600 KYFAKSQSKI 610 TRLITAVVMK 620 DWKEIVESCD 630 LKNWREALAA 640 VLTYAKPDEF 650 SALCDLLGTR 660 LESEGDSLLQ 670 TQACLCYICA 680 GNVEKLVACW 690 TKAQDGSNPL 700 SLQDLIEKVV 710 ILRRAVQLTQ 720 AVDTNAVGVL 730 LAEKMSQYAS 740 LLAAQGSIAA 750 ALAFLPENTN 760 QPNIVQLRDR 770 LCRAQGDPAP 780 GHQESPKSPY 790 ERQQLPKGRP 800 GPVAGHTQMP 810 RVPAQQYYPH 820 GENPPPPAFV 830 MHGSGHPNAG 840 APTPLGHVHT 850 QVPPYPQPQP 860 YQPAQQYSLG 870 TGGSAVYRPQ 880 QPVAPSASNT 890 YPNTPYISSA 900 SSYPGQSQLY 910 TAQHQASPPT 920 SSPTASFPLP 930 PSSGASFQHG 940 GPGAPPSSSA 950 YALPPGTTES 960 QSMPDQASVL 970 EGPQNGWNDP 980 PALNRVPKKK 990 KMPENFTPPV 1000 PITSPIMNPL 1010 GDPQSQMLQQ 1020 QPSAPVPLSS 1030 QASFLQPHLP 1040 GGQPFHGILQ 1050 PLGQVGMPPS 1060 FSKPNVEGAP 1070 GAPIGNTIQH 1080 VQSLPTEKIT 1090 KKPIPDEHLV 1100 LKTTFEDLIQ 1110 RCLSSATDPQ 1120 TKRKLDDASK 1130 RLEFLYDKLR 1140 EQTLSPTIIS 1150 GLHNIARSIE 1160 TRNYSKGLTI 1170 HTHVVSTSNF 1180 SETSAFMPVL 1190 KVVLTQAIKL GV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0012507 ER to Golgi transport vesicle membrane
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0015031 protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.