Search Results
Overview
| Uniprot ID | A0A288CFV5 |
|---|---|
| Protein Name | Serotransferrin |
| Gene Name | TF |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 580 | AFRCLVEKGDVAFVK |
Function
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation
Protein Sequence
10
MWMFISFPES
20
ALCCGSRVEM
30
TEGFGSNAKT
40
QFMGTRYLQP
50
GLSLAVAQKT
60
VRWCTISNQE
70
ANKCSSFREN
80
MSKAVKNGPL
90
VSCVKKSSYL
100
DCIKAIRDKE
110
ADAVTLDAGL
120
VFEAGLAPYN
130
LKPVVAEFYG
140
QKDNPQTHYY
150
AVAVVKKGSN
160
FQWNQLQGKR
170
SCHTGLGRSA
180
GWIIPMGLLY
190
DQLPEPRKPI
200
EKAVASFFSS
210
SCVPCADPVN
220
FPKLCQQCAG
230
KGAEKCACSN
240
HEPYFGYAGA
250
FNCLKEDAGD
260
VAFVKHSTVL
270
ENLPDKADRD
280
QYELLCRDNT
290
RRPVDDYENC
300
YLAQVPSHAV
310
VARSVDGQED
320
SIWELLNQAQ
330
EHFGRDKSPD
340
FQLFSSSHGK
350
DLLFKDSANG
360
FKIPSKMDSS
370
LYLGYQYVTA
380
LRNLREEISP
390
DSSKNECKKV
400
RWCAIGHEET
410
QKCDAWSINS
420
GGKIECVSAE
430
NTEDCIAKIV
440
KGEADAMSLD
450
GGYIYIAGKC
460
GLVPVLAENY
470
KTEGENCVNT
480
PEKGYLAVAV
490
VKKSSGPDLN
500
WNNLKGKKSC
510
HTAVDRTAGW
520
NIPMGLLYNK
530
INSCKFDQFF
540
GEGCAPGSQR
550
NSSLCALCIG
560
SERAPGRECL
570
ANNHERYYGY
580
TGAFRCLVEK
590
GDVAFVKDQV
600
VQQNTDGKNK
610
DDWAKDLKQM
620
DFELLCQNGA
630
REPVDNAENC
640
HLARAPNHAV
650
VARDDKVTCV
660
AEELLKQQAQ
670
FGRHVTDCSS
680
SFCMFKSNTK
690
DLLFRDDTQC
700
LARVGKTTYE
710
SYLGADYITA
720
VANLRKCSTS
730
KLLEACTFHS
740
AKNPRVETTT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016324 | apical plasma membrane |
| Cellular Component | GO:0009925 | basal plasma membrane |
| Cellular Component | GO:0009986 | cell surface |
| Cellular Component | GO:0005905 | clathrin-coated pit |
| Cellular Component | GO:0005769 | early endosome |
| Cellular Component | GO:0030139 | endocytic vesicle |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:1990712 | HFE-transferrin receptor complex |
| Cellular Component | GO:0005770 | late endosome |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0055037 | recycling endosome |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0008199 | ferric iron binding |
| Molecular Function | GO:0008198 | ferrous iron binding |
| Molecular Function | GO:0034986 | iron chaperone activity |
| Molecular Function | GO:1990459 | transferrin receptor binding |
| Molecular Function | GO:0044325 | transmembrane transporter binding |
| Biological Process | GO:0019731 | antibacterial humoral response |
| Biological Process | GO:0007166 | cell surface receptor signaling pathway |
| Biological Process | GO:0071281 | cellular response to iron ion |
| Biological Process | GO:0006879 | intracellular iron ion homeostasis |
| Biological Process | GO:0006826 | iron ion transport |
| Biological Process | GO:0060586 | multicellular organismal-level iron ion homeostasis |
| Biological Process | GO:0051241 | negative regulation of multicellular organismal process |
| Biological Process | GO:0030316 | osteoclast differentiation |
| Biological Process | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| Biological Process | GO:0048260 | positive regulation of receptor-mediated endocytosis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.