Search Results

Overview

Uniprot IDA0A2C9F371
Protein NameGonadotropin-releasing hormone receptor
Gene NameUBA6
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
1352 LTMHKLVKPSTEKKY
633 AVQVKTPKTFCFEPL
690 IGCQQDSKELLKLAT

Function

Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system

Protein Sequence

10 MANSASPEQN 20 QNHCSAINSS 30 ILLTQGNLPT 40 LTLSGKIRVT 50 VTFFLFLLST 60 AFNASFLLKL 70 QKWTQRKEKG 80 KKLSRMKVLL 90 KHLTLANLLE 100 TLIVMPLDGM 110 WNITVQWYAG 120 EFLCKVLSYL 130 KLFSMYAPAF 140 MMVVISLDRS 150 LAITRPLAVK 160 SNSRLGRFMI 170 GLAWLLSSIF 180 AGPQLYIFRM 190 IHLADSSGQT 200 EGFSQCVTHG 210 SFPQWWHQAF 220 YNFFTFSCLF 230 IIPLLIMLIC 240 NAKIMFTLTR 250 VLQQDPHNLQ 260 LNQSKNNIPR 270 ARLRTLKMTV 280 AFAASFIVCW 290 TPYYVLGIWC 300 HVPSAFRLRL 310 YPPDPSPNSA 320 ATATTCSKAR 330 PSTTPKPEAR 340 TPLGLTGRRR 350 QADLSPPAPS 360 GDVTARPLTS 370 RPRPLPCLRW 380 SAAAESQETM 390 EGSQPVATHQ 400 GEEASCSSWG 410 PGSVNTNLPI 420 MPTESVEIDD 430 ALYSRQRYVL 440 GDTAMQKMAR 450 SHVFLSGMGG 460 LGLEIAKNLV 470 LAGIKAVTIH 480 DTEKCQAWDL 490 GTNFFLCEDD 500 VVNSRNRAEA 510 VLQHIAELNP 520 YVHVTSSSVP 530 LNESTDLSFL 540 DKYQCVVLTE 550 IKLPLRKKIN 560 DFCRSQCPPI 570 KANPGIVTCL 580 ENHPHKLETG 590 QFLTFREING 600 MTGLNGSTQQ 610 ITVISPFSFS 620 IGDTTGLEPY 630 LHGGIAVQVK 640 TPKTFCFEPL 650 EKQIKHPKCL 660 IADFSKPEAS 670 LEIHSAMLAL 680 DQFQENYSRK 690 PNIGCQQDSK 700 ELLKLATSIC 710 ETLEEKPEVN 720 NDIVRWLSWT 730 AQGFLPPLAA 740 TVGGLASQEV 750 LKAVTGKFSP 760 LCQWLYIEAA 770 DIVESLDKPE 780 REEFLPRGDR 790 YDALRACIGD 800 TLCQKLQNLN 810 IFLVGCGAIG 820 CEMLKNFALL 830 GVGTGKEKGM 840 VTVTDPDLIE 850 KSNLNRQFLF 860 RPHHIQKPKS 870 YTAADATLKI 880 NPQLKIDAHL 890 NKVCSATEAI 900 YNDEFYTKQD 910 IIITALDNVE 920 ARRYVDSRCL 930 ANLRPLLDSG 940 TMGTKGHTEV 950 IVPHLTESYN 960 SHRDPPEEEI 970 PFCTLKSFPA 980 AIEHTIQWAR 990 DKFESSFSYK 1000 PSLFNKFWQT 1010 YSSAEEVLQK 1020 IQTGHSLEGC 1030 FQVIKLLSRR 1040 PRNWTQCVEL 1050 ARLKFEKYFN 1060 HKALQLLHCF 1070 PLDTRLKDGS 1080 LFWQSPKRPP 1090 SPLKFDLNEP 1100 LHLSFLLNAA 1110 KLYATVYCIP 1120 YTEEDLSADT 1130 LLNILSEVKI 1140 QEFKPSNKVV 1150 QTDETARKPD 1160 HVPISSEDER 1170 NAIFQLEKAI 1180 SSNEATASDL 1190 QMAVLSFEKD 1200 DDRNGHIDFI 1210 TAASNLRAKM 1220 YSIEPADRLK 1230 TKRIAGRIIP 1240 AIATSTAAVS 1250 GLVALEMIKV 1260 AGDYPFEAYK 1270 NCFLNLAIPI 1280 IVFTETSEVR 1290 KTEIRNGISF 1300 TIWDRWTIHG 1310 KEDFTLLDFI 1320 NAVKEKYGIE 1330 PTMVVQGVKM 1340 LYVPVMPGHA 1350 KRLKLTMHKL 1360 VKPSTEKKYV 1370 DLTVSFAPDT 1380 DGDEDLPGPP 1390 VRYYFSHDTD

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0019780 FAT10 activating enzyme activity
Molecular Function GO:0004930 G protein-coupled receptor activity
Molecular Function GO:0046872 metal ion binding
Molecular Function GO:0016500 protein-hormone receptor activity
Molecular Function GO:0004839 ubiquitin activating enzyme activity
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.