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Overview

Uniprot IDA0A2C9F380
Protein NamePhosphoacetylglucosamine mutase
Gene NamePGM3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
196 TAFVELSKQASCSGD
209 GDDHRTLKVDCANGI
349 KVPVYCTKTGVKHLH

Function

Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation

Protein Sequence

10 MDLDAITKHS 20 ASHAKPDGLI 30 LQYGTAGFRT 40 KADRLDHVMF 50 RMGLLAVLRS 60 KQTKSTIGVM 70 VTASHNPEDD 80 NGVKLVDPLG 90 EMLAPSWEEH 100 ATHLANAEEQ 110 DLARALVAIS 120 EEAAVNLHQD 130 AFVVIGRDTR 140 PSSEKLSESV 150 IDGVTVLGGQ 160 FHDYGLLTTP 170 QLHYMVCCRN 180 TGGQYGEATI 190 DGYYHKLSTA 200 FVELSKQASC 210 SGDDHRTLKV 220 DCANGIGALK 230 LKEMKHYLPQ 240 GLSVQLFNDG 250 TKKLNHFCGA 260 DFVKSHQKPP 270 EGIEMKANER 280 CCSFDGDADR 290 IIYYYCDVDG 300 HFHLIDGDKI 310 ATLISSFLKE 320 LLLEIGESLT 330 VGVVQTAYAN 340 GSSTRYLEEV 350 MKVPVYCTKT 360 GVKHLHHKAQ 370 EFDLGVYFEA 380 NGHGTVLFSK 390 AAEAKIRQLA 400 KELEDKKGKA 410 AKMLENVIDL 420 FNQATGDAIS 430 DMLVIEAILA 440 LKGLTIQQWD 450 ALYTDLPNRQ 460 LKVKVADRQV 470 ISTTDAERQV 480 VKPPGLQEAI 490 NDLVKKYKLS 500 RAFVRPSGTE 510 DVVRVYAEAD 520 SQVRKCQPCI

Gene Ontology

Classification GO ID Description
Molecular Function GO:0000287 magnesium ion binding
Molecular Function GO:0004610 phosphoacetylglucosamine mutase activity
Biological Process GO:0005975 carbohydrate metabolic process
Biological Process GO:0006048 UDP-N-acetylglucosamine biosynthetic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.