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Overview

Uniprot IDA0A3B6EFT7
Protein NameSplicing factor YJU2
Gene Name-
OrganismTriticum aestivum

Kla Sites from experimental identification

Position Flanking peptide
27 IPRRKQPKNQQIKVR

Function

Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates

Protein Sequence

10 MGERKVLNKY 20 YPPDFDPAKI 30 PRRKQPKNQQ 40 IKVRMMHPMS 50 IRCGTCGTYI 60 YKGTKFNSRK 70 EDCIGETYLG 80 IQIFRFYFKC 90 TRCSAEITFK 100 TDPQNSDYTV 110 ESGASRNFEP 120 WREEDEVVDK 130 EKRKREAEEM 140 GDAMRALENR 150 AMDSKQDMDI 160 LAALEEMRSM 170 KSRHAGVSVD 180 QMLEILKHSA 190 HQKEEKTVAE 200 LDEEDEELIK 210 SITFNSKDYV 220 KRIEDDDDDD 230 DDDNFGIPGQ 240 SSVTSKQING 250 SSESMTNPTD 260 VLTKANGPES 270 ANKEPKNLTL 280 NSASAEPHKS 290 VHAASRGLLV ERSL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0071006 U2-type catalytic step 1 spliceosome
Molecular Function GO:0046872 metal ion binding
Biological Process GO:0000349 generation of catalytic spliceosome for first transesterification step
Biological Process GO:0045292 mRNA cis splicing, via spliceosome

Reference

[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.