Search Results
Overview
| Uniprot ID | A0A3B6IJZ7 |
|---|---|
| Protein Name | Core Histone H2A/H2B/H3 domain-containing protein |
| Gene Name | LOC123094127 |
| Organism | Triticum aestivum |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 16 | KVVSSVVKTKVVEET |
| 9 | APKRRGSKVVSSVVK |
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Protein Sequence
10
MAPKRRGSKV
20
VSSVVKTKVV
30
EETVEVATTI
40
LPASQSQSQP
50
DSAAQEEDLQ
60
QPEVVDVSRS
70
RDVHVEVVTT
80
PDAQPTHGAK
90
KQPASKRGAA
100
NAKPPAGPLV
110
VPVSPSPQEQ
120
EAQPAEEQQQ
130
QRKKGGGKTP
140
ASLQSQETQE
150
NPYAYQDETT
160
KKRPAEEDDG
170
AEPNKPEGPE
180
TPTQKRSRTE
190
GKAKTRKAEA
200
AARKKLSAAA
210
GKGKGGRRRR
220
RLGGNNVDMG
230
YKAYVYRVLK
240
QVHPDLGASG
250
KTMQALDMMM
260
ADMFERLATE
270
ASRLAQYAGR
280
ATLTSRDVQN
290
AVRLVLPGEL
300
AKHAISEGTK
AVTMYMS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000786 | nucleosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0030527 | structural constituent of chromatin |
| Biological Process | GO:0006325 | chromatin organization |
Reference
[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.