Search Results
Overview
| Uniprot ID | A0A3B6KPW7 |
|---|---|
| Protein Name | Histone H2A |
| Gene Name | LOC123108116 |
| Organism | Triticum aestivum |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 35 | QAVARSVKAGLQFPV |
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Protein Sequence
10
MEASAAGAVA
20
KAKKYVVGRK
30
LGGGPRKQAV
40
ARSVKAGLQF
50
PVGRIGRFLK
60
KGRYAQRVGM
70
GAPVYLASVL
80
EYLAAELLEL
90
AGNAAKDNKK
100
SRIIPRHLLL
110
AIRNDQELGR
120
LLAGVTIAHG
130
GVLPNINPVL
140
LPKKAADKEP
150
KSPKKAAKSP
KKA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000792 | heterochromatin |
| Cellular Component | GO:0000786 | nucleosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0030527 | structural constituent of chromatin |
| Biological Process | GO:0031507 | heterochromatin formation |
Reference
[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.