Search Results
Overview
| Uniprot ID | A0A3B6QFG6 |
|---|---|
| Protein Name | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial |
| Gene Name | LOC123144854 |
| Organism | Triticum aestivum |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 119 | LNQVLVTKQTGPQGK |
| 179 | VVDGLAPKTADRQSS |
| 392 | DAAEKAVKASVK*** |
| 59 | VGSVQEVKEVLKNVF |
| 70 | KNVFPSEKEIVVKSQ |
Function
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
Protein Sequence
10
MVRGSLGRLA
20
SRTLSVAGKW
30
QHQQLRRLNI
40
HEYQGAELMG
50
KFGINVPKGA
60
VVGSVQEVKE
70
VLKNVFPSEK
80
EIVVKSQILA
90
GGRGLGTFKS
100
GLKGGVHIVK
110
AEEAESLAAK
120
MLNQVLVTKQ
130
TGPQGKVVGK
140
LIIACAEGGT
150
SIEDLAEKFP
160
DKIVKVPVDV
170
FKGITDEDAA
180
KVVDGLAPKT
190
ADRQSSIEQI
200
KKLYELFCKT
210
DCTMLEINPL
220
AETADKKLVA
230
ADAKLNFDDN
240
AAFRQKEIFA
250
LRDTTQEDPR
260
EVAAAKADLN
270
YIGLDGEIGC
280
MVNGAGLAMA
290
TMDIIKLHGG
300
TPANFLDVGG
310
SASEGQVVEA
320
FKILTSDDRV
330
KAILVNIFGG
340
IMKCDVIASG
350
IVNAAKQVDL
360
KVPVVVRLEG
370
TNVDQGKRIL
380
KESGMTLITA
390
EDLDDAAEKA
VKASVK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0004775 | succinate-CoA ligase (ADP-forming) activity |
| Biological Process | GO:0006099 | tricarboxylic acid cycle |
Reference
[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.