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Overview

Uniprot IDA0A3B6RCH0
Protein NameADP/ATP translocase
Gene NameLOC123154247
OrganismTriticum aestivum

Kla Sites from experimental identification

Position Flanking peptide
114 QNQDEMIKSGRLSHP
219 ANDAKAAKVGGQRQF

Function

ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane

Protein Sequence

10 MDELCPPYVV 20 QKLHGQSMLL 30 RQISSSATRS 40 HVINNAHYAR 50 NFSVTKYHQT 60 NGSIGRLPRN 70 TPSPIRAPAP 80 EEKGFSGFMI 90 DFLMGGVSAA 100 VSKTAAAPIE 110 RVKLLIQNQD 120 EMIKSGRLSH 130 PYKSIGDCFT 140 RTIKDEGVVA 150 LWRGNTANVI 160 RYFPTQALNF 170 AFKDHFKRMF 180 NFRKDKDGYW 190 KWFFGNIASG 200 GAAGASSLLF 210 VYSLDYARTR 220 LANDAKAAKV 230 GGQRQFDGIV 240 DVYRKTLASD 250 GVRGLYRGFN 260 VSCVGIIVYR 270 GLYFGMYDSL 280 KPAVLVGSLE 290 DNLLASFLLG 300 WGVTMGAGLA 310 SYPIDTVRRR 320 MMMTSGESVK 330 YKNSMDAFRK 340 IIAEEGAKSL 350 FKGAGANILR 360 AVAGAGVLAV 370 YDKLQVVVFG KKYGSGGG

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005757 mitochondrial permeability transition pore complex
Molecular Function GO:0005471 ATP:ADP antiporter activity
Biological Process GO:0140021 mitochondrial ADP transmembrane transport
Biological Process GO:1990544 mitochondrial ATP transmembrane transport
Biological Process GO:0046902 regulation of mitochondrial membrane permeability

Reference

[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.