Search Results
Overview
| Uniprot ID | A0A480KCY2 |
|---|---|
| Protein Name | Prolyl 3-hydroxylase OGFOD1 |
| Gene Name | OGFOD1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 117 | PHICALRKILFEHFR |
Function
Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation
Protein Sequence
10
MNGKRSTELG
20
PGRAGKKVKK
30
EVMANISDAV
40
TEETLKKQVA
50
EAWSRRTPFR
60
HEAIVMDMDP
70
FLHCVIPNFI
80
QSQSFLEGLQ
90
KELLNLDFHE
100
KYNDLYKFQQ
110
SDDLKKRREP
120
HICALRKILF
130
EHFRAWLSDI
140
SKIDLESTID
150
MSCAKYEFSD
160
ALLCHDDELE
170
GRRIAFILYL
180
VPPWDRSLGG
190
TLDMYSVDEH
200
FQPKQIVKSL
210
IPSWNTLVFF
220
EVSPISFHQV
230
SEVLSEEKSR
240
LSISGWFHGP
250
SLTRPPTYFE
260
PLLPRSPHIP
270
QDHEVLCDWI
280
NPTYLDMEYQ
290
VQIQEEFEES
300
SEILLKEFLK
310
PEKFAEVCEA
320
LEKGDVEWTS
330
QGPPNKRFYE
340
KAEESKLPKI
350
LKDCMALFRS
360
EAMFLLLSNF
370
TGLKLHFLAP
380
SEEDELEDKK
390
EGEAASPADN
400
TEEGTSHSSF
410
EPENSREAIS
420
DSSQQSNEQI
430
DPEPEETKAK
440
KESSVPTCQG
450
ELRHWKTGHY
460
TLIHDNTKTE
470
FALDLLLYCG
480
CEGWEPEYGG
490
FTSYIAKGED
500
EELLTVNPEN
510
NSLALVYRDR
520
ETLKFVKHIN
530
HRSLEQKKTF
540
PNRTGFWNFS
FVYYE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0010494 | cytoplasmic stress granule |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0005506 | iron ion binding |
| Molecular Function | GO:0031418 | L-ascorbic acid binding |
| Molecular Function | GO:0031544 | peptidyl-proline 3-dioxygenase activity |
| Molecular Function | GO:0031543 | peptidyl-proline dioxygenase activity |
| Biological Process | GO:0008283 | cell population proliferation |
| Biological Process | GO:0006449 | regulation of translational termination |
| Biological Process | GO:0034063 | stress granule assembly |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.